LOCUS 1F76_A 336 aa linear BCT 01-DEC-2020
DEFINITION Chain A, Dihydroorotate dehydrogenase (quinone).
ACCESSION 1F76_A
VERSION 1F76_A
DBSOURCE pdb: molecule 1F76, chain A, release Mar 12, 2014;
deposition: Jun 26, 2000;
class: Oxidoreductase;
source: Mmdb_id: 20764, Pdb_id 1: 1F76;
Exp. method: X-Ray Diffraction.
KEYWORDS .
SOURCE Escherichia coli K-12
ORGANISM Escherichia coli K-12
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE 1 (residues 1 to 336)
AUTHORS Bjornberg,O., Jensen,K.F., Gruner,A.-C., Ottosen,M., Sore,P.,
Rowland,P., Norager,S. and Larsen,S.
TITLE The Dihydroorotate Dehydrogenases Of Escherichia Co Lactococcus
Lactis Represent Two Distinct Families Enzyme
JOURNAL Flavins And Flavoproteins,Proc.13th Int.Symp., 607 (1999)
REFERENCE 2 (residues 1 to 336)
AUTHORS Palfey,B., Bjornberg,O. and Jensen,K.F.
TITLE Reduction Reactions Of Two Dihydroorotate Dehydroge
JOURNAL Flavins And Flavoproteins,Proc.13th Int.Symp., 615 (1999)
REFERENCE 3 (residues 1 to 336)
AUTHORS Bjornberg,O., Gruner,A.C., Roepstorff,P. and Jensen,K.F.
TITLE The activity of Escherichia coli dihydroorotate dehydrogenase is
dependent on a conserved loop identified by sequence homology,
mutagenesis, and limited proteolysis
JOURNAL Biochemistry 38 (10), 2899-2908 (1999)
PUBMED 10074342
REFERENCE 4 (residues 1 to 336)
AUTHORS Rowland,P., Norager,S., Jensen,K.F. and Larsen,S.
TITLE Crystallization and preliminary X-ray studies of
membrane-associated Escherichia coli dihydroorotate dehydrogenase
JOURNAL Acta Crystallogr. D Biol. Crystallogr. 56 (PT 5), 659-661 (2000)
PUBMED 10771442
REFERENCE 5 (residues 1 to 336)
AUTHORS Norager,S., Jensen,K.F., Bjornberg,O. and Larsen,S.
TITLE E. coli dihydroorotate dehydrogenase reveals structural and
functional distinctions between different classes of dihydroorotate
dehydrogenases
JOURNAL Structure 10 (9), 1211-1223 (2002)
PUBMED 12220493
REFERENCE 6 (residues 1 to 336)
AUTHORS Norager,S., Jensen,K.F., Bjornberg,O. and Larsen,S.
TITLE Direct Submission
JOURNAL Submitted (26-JUN-2000)
COMMENT Escherichia Coli Dihydroorotate Dehydrogenase.
FEATURES Location/Qualifiers
source 1..336
/organism="Escherichia coli K-12"
/db_xref="taxon:83333"
NonStdRes 1
/non_std_residue="MSE NH3+"
Het bond(1)
/heterogen="(ORO,1002)"
Region 2..336
/region_name="PRK05286"
/note="quinone-dependent dihydroorotate dehydrogenase"
/db_xref="CDD:235388"
SecStr 3..11
/sec_str_type="helix"
/note="helix 1"
SecStr 15..29
/sec_str_type="helix"
/note="helix 2"
SecStr 46..50
/sec_str_type="sheet"
/note="strand 1"
NonStdRes 50
/non_std_residue="MSE"
SecStr 51..55
/sec_str_type="sheet"
/note="strand 2"
SecStr 57..63
/sec_str_type="sheet"
/note="strand 3"
SecStr 70..77
/sec_str_type="helix"
/note="helix 3"
NonStdRes 77
/non_std_residue="MSE"
SecStr 80..85
/sec_str_type="sheet"
/note="strand 4"
SecStr 89..94
/sec_str_type="sheet"
/note="strand 5"
SecStr 99..104
/sec_str_type="sheet"
/note="strand 6"
SecStr 107..112
/sec_str_type="sheet"
/note="strand 7"
NonStdRes 113
/non_std_residue="MSE"
SecStr 115..120
/sec_str_type="sheet"
/note="strand 8"
SecStr 121..129
/sec_str_type="helix"
/note="helix 4"
SecStr 134..141
/sec_str_type="sheet"
/note="strand 9"
SecStr 153..162
/sec_str_type="helix"
/note="helix 5"
NonStdRes 159
/non_std_residue="MSE"
SecStr 167..172
/sec_str_type="sheet"
/note="strand 10"
SecStr 188..208
/sec_str_type="helix"
/note="helix 6"
NonStdRes 207
/non_std_residue="MSE"
SecStr 213..218
/sec_str_type="sheet"
/note="strand 11"
SecStr 224..237
/sec_str_type="helix"
/note="helix 7"
SecStr 240..244
/sec_str_type="sheet"
/note="strand 12"
NonStdRes 257
/non_std_residue="MSE"
SecStr 264..269
/sec_str_type="sheet"
/note="strand 13"
SecStr 272..286
/sec_str_type="helix"
/note="helix 8"
SecStr 290..295
/sec_str_type="sheet"
/note="strand 14"
SecStr 301..310
/sec_str_type="helix"
/note="helix 9"
SecStr 313..317
/sec_str_type="sheet"
/note="strand 15"
SecStr 327..335
/sec_str_type="helix"
/note="helix 10"
ORIGIN
1 xyypfvrkal fqldperahe ftfqqlrrit gtpfealvrq kvpakpvncx gltfknplgl
61 aagldkdgec idalgaxgfg sieigtvtpr pqpgndkprl frlvdaegli nrxgfnnlgv
121 dnlvenvkka hydgvlgini gknkdtpveq gkddylicxe kiyayagyia inisspntpg
181 lrtlqygeal ddlltaiknk qndlqaxhhk yvpiavkiap dlseeeliqv adslvrhnid
241 gviatnttld rslvqgxknc dqtgglsgrp lqlksteiir rlslelngrl piigvggids
301 viaarekiaa gaslvqiysg fifkgpplik eivthi
//