RecName: Full=Presenilin-2; Short=PS-2; AltName: Full=AD3LP; AltName: - Protein

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Quantitative comparison of presenilin protein expression reveals greater activity of PS2-γ-secretase. [FASEB J. 2024]
Quantitative comparison of presenilin protein expression reveals greater activity of PS2-γ-secretase.
Eccles MK, Main N, Carlessi R, Armstrong AM, Sabale M, Roberts-Mok B, Tirnitz-Parker JEE, Agostino M, Groth D, Fraser PE, et al. FASEB J. 2024 Jan; 38(1):e23396.
PSEN2 Mutation Spectrum and Novel Functionally Validated Mutations in Alzheimer's Disease: Data from PUMCH Dementia Cohort. [J Alzheimers Dis. 2022]
PSEN2 Mutation Spectrum and Novel Functionally Validated Mutations in Alzheimer's Disease: Data from PUMCH Dementia Cohort.
Dong L, Liu C, Sha L, Mao C, Li J, Huang X, Wang J, Chu S, Peng B, Cui L, et al. J Alzheimers Dis. 2022; 87(4):1549-1556.
A Rare Variation in the 3' Untranslated Region of the Presenilin 2 Gene Is Linked to Alzheimer's Disease. [Mol Neurobiol. 2021]
A Rare Variation in the 3' Untranslated Region of the Presenilin 2 Gene Is Linked to Alzheimer's Disease.
Pang Y, Li T, Wang Q, Qin W, Li Y, Wei Y, Jia L. Mol Neurobiol. 2021 Sep; 58(9):4337-4347. Epub 2021 May 19.

RefSeq genomic sequence
See the genomic reference sequence for the PSEN2 gene (NG_007381.2).
RefSeq protein isoforms
See 12 reference sequence protein isoforms for the PSEN2 gene.

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P49810 [Domain Mapping of Disease Mut...]
P49810
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome

RecName: Full=Presenilin-2; Short=PS-2; AltName: Full=AD3LP; AltName: Full=AD5; ...
RecName: Full=Presenilin-2; Short=PS-2; AltName: Full=AD3LP; AltName: Full=AD5; AltName: Full=E5-1; AltName: Full=STM-2; Contains: RecName: Full=Presenilin-2 NTF subunit; Contains: RecName: Full=Presenilin-2 CTF subunit
gi|1709858|sp|P49810.1|PSN2_HUMAN

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