RecName: Full=Dual specificity mitogen-activated protein kinase kinase - Protein

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Monocytic cell differentiation from band-stage neutrophils under inflammatory conditions via MKK6 activation. [Blood. 2014]
Monocytic cell differentiation from band-stage neutrophils under inflammatory conditions via MKK6 activation.
Köffel R, Meshcheryakova A, Warszawska J, Hennig A, Wagner K, Jörgl A, Gubi D, Moser D, Hladik A, Hoffmann U, et al. Blood. 2014 Oct 23; 124(17):2713-24. Epub 2014 Sep 11.
MKK6 is upregulated in human esophageal, stomach, and colon cancers. [Cancer Invest. 2014]
MKK6 is upregulated in human esophageal, stomach, and colon cancers.
Parray AA, Baba RA, Bhat HF, Wani L, Mokhdomi TA, Mushtaq U, Bhat SS, Kirmani D, Kuchay S, Wani MM, et al. Cancer Invest. 2014 Oct; 32(8):416-22. Epub 2014 Jul 14.
Crystal structure of non-phosphorylated MAP2K6 in a putative auto-inhibition state. [J Biochem. 2012]
Crystal structure of non-phosphorylated MAP2K6 in a putative auto-inhibition state.
Matsumoto T, Kinoshita T, Matsuzaka H, Nakai R, Kirii Y, Yokota K, Tada T. J Biochem. 2012 May; 151(5):541-9. Epub 2012 Mar 1.

RefSeq genomic sequence
See the genomic reference sequence for the MAP2K6 gene (NG_029437.2).
RefSeq protein isoforms
See 12 reference sequence protein isoforms for the MAP2K6 gene.

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P52564 [Domain Mapping of Disease Mut...]
P52564
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

RecName: Full=Dual specificity mitogen-activated protein kinase kinase 6; Short=...
RecName: Full=Dual specificity mitogen-activated protein kinase kinase 6; Short=MAP kinase kinase 6; Short=MAPKK 6; AltName: Full=MAPK/ERK kinase 6; Short=MEK 6; AltName: Full=Stress-activated protein kinase kinase 3; Short=SAPK kinase 3; Short=SAPKK-3; Short=SAPKK3
gi|1709088|sp|P52564.1|MP2K6_HUMAN

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