RecName: Full=Polyunsaturated fatty acid lipoxygenase ALOX12; AltName: - Protein

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A small molecule targeting ALOX12-ACC1 ameliorates nonalcoholic steatohepatitis in mice and macaques. [Sci Transl Med. 2021]
A small molecule targeting ALOX12-ACC1 ameliorates nonalcoholic steatohepatitis in mice and macaques.
Zhang XJ, Ji YX, Cheng X, Cheng Y, Yang H, Wang J, Zhao LP, Huang YP, Sun D, Xiang H, et al. Sci Transl Med. 2021 Dec 15; 13(624):eabg8116. Epub 2021 Dec 15.
Multiple omics study identifies an interspecies conserved driver for nonalcoholic steatohepatitis. [Sci Transl Med. 2021]
Multiple omics study identifies an interspecies conserved driver for nonalcoholic steatohepatitis.
Zhang XJ, She ZG, Wang J, Sun D, Shen LJ, Xiang H, Cheng X, Ji YX, Huang YP, Li PL, et al. Sci Transl Med. 2021 Dec 15; 13(624):eabg8117. Epub 2021 Dec 15.
Hydrogen sulfide guards myoblasts from ferroptosis by inhibiting ALOX12 acetylation. [Cell Signal. 2021]
Hydrogen sulfide guards myoblasts from ferroptosis by inhibiting ALOX12 acetylation.
Wang Y, Yu R, Wu L, Yang G. Cell Signal. 2021 Feb; 78:109870. Epub 2020 Dec 5.

RefSeq protein isoforms
See 2 reference sequence protein isoforms for the Alox12 gene.

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Mouse Genome Informatics (MGI) [Mouse Genome Informatics (MGI)]
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PANTHER Classification System
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ExactAntigen/Labome

RecName: Full=Polyunsaturated fatty acid lipoxygenase ALOX12; AltName: Full=Arac...
RecName: Full=Polyunsaturated fatty acid lipoxygenase ALOX12; AltName: Full=Arachidonate (12S)-lipoxygenase; Short=12S-LOX; Short=12S-lipoxygenase; AltName: Full=Arachidonate (15S)-lipoxygenase; AltName: Full=Linoleate (13S)-lipoxygenase; AltName: Full=Lipoxin synthase 12-LO; AltName: Full=Platelet-type lipoxygenase 12; Short=P-12LO
gi|158518404|sp|P39655.4|LOX12_MOUS

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