RecName: Full=Mothers against decapentaplegic homolog 4; Short=MAD hom - Protein

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SMAD4 depletion contributes to endocrine resistance by integrating ER and ERBB signaling in HR + HER2- breast cancer. [Cell Death Dis. 2024]
SMAD4 depletion contributes to endocrine resistance by integrating ER and ERBB signaling in HR + HER2- breast cancer.
Li K, Shu D, Li H, Lan A, Zhang W, Tan Z, Huang M, Tomasi ML, Jin A, Yu H, et al. Cell Death Dis. 2024 Jun 24; 15(6):444. Epub 2024 Jun 24.
Functional filter for whole-genome sequencing data identifies HHT and stress-associated non-coding SMAD4 polyadenylation site variants >5 kb from coding DNA. [Am J Hum Genet. 2023]
Functional filter for whole-genome sequencing data identifies HHT and stress-associated non-coding SMAD4 polyadenylation site variants >5 kb from coding DNA.
Xiao S, Kai Z, Murphy D, Li D, Patel D, Bielowka AM, Bernabeu-Herrero ME, Abdulmogith A, Mumford AD, Westbury SK, et al. Am J Hum Genet. 2023 Nov 2; 110(11):1903-1918. Epub 2023 Oct 9.
Methylation status, mRNA and protein expression of the SMAD4 gene in patients with non-melanocytic skin cancers. [Mol Biol Rep. 2023]
Methylation status, mRNA and protein expression of the SMAD4 gene in patients with non-melanocytic skin cancers.
Gürsel Ürün Y, Budak M, Usturalı Keskin E. Mol Biol Rep. 2023 Sep; 50(9):7295-7304. Epub 2023 Jul 10.

RefSeq genomic sequence
See the genomic reference sequence for the SMAD4 gene (NG_013013.2).
RefSeq protein isoforms
See 4 reference sequence protein isoforms for the SMAD4 gene.

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Q13485 [Domain Mapping of Disease Mut...]
Q13485
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome

RecName: Full=Mothers against decapentaplegic homolog 4; Short=MAD homolog 4; Sh...
RecName: Full=Mothers against decapentaplegic homolog 4; Short=MAD homolog 4; Short=Mothers against DPP homolog 4; AltName: Full=Deletion target in pancreatic carcinoma 4; AltName: Full=SMAD family member 4; Short=SMAD 4; Short=Smad4; Short=hSMAD4
gi|13959561|sp|Q13485.1|SMAD4_HUMAN

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