RecName: Full=Cyclin-dependent kinase 12; AltName: Full=Cdc2-related k - Protein

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CDK12 inhibition mediates DNA damage and is synergistic with sorafenib treatment in hepatocellular carcinoma. [Gut. 2020]
CDK12 inhibition mediates DNA damage and is synergistic with sorafenib treatment in hepatocellular carcinoma.
Wang C, Wang H, Lieftink C, du Chatinier A, Gao D, Jin G, Jin H, Beijersbergen RL, Qin W, Bernards R. Gut. 2020 Apr; 69(4):727-736. Epub 2019 Sep 13.
Identification of a novel protein for memory regulation in the hippocampus. [Biochem Biophys Res Commun. 2005]
Identification of a novel protein for memory regulation in the hippocampus.
Zhang XH, Zhang H, Tu Y, Gao X, Zhou C, Jin M, Zhao G, Jing N, Li BM, Yu L. Biochem Biophys Res Commun. 2005 Aug 26; 334(2):418-24.
Low expression of CDK12 in gastric cancer is correlated with advanced stage and poor outcome. [Pathol Res Pract. 2020]
Low expression of CDK12 in gastric cancer is correlated with advanced stage and poor outcome.
Liu M, Fan H, Li T, Sihong L, Qiao S, Bi J. Pathol Res Pract. 2020 Jul; 216(7):152962. Epub 2020 May 7.

RefSeq protein isoforms
See 10 reference sequence protein isoforms for the Cdk12 gene.

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Transcript/Protein Information [PANTHER Classification System]
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PANTHER Classification System
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Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

RecName: Full=Cyclin-dependent kinase 12; AltName: Full=Cdc2-related kinase, arg...
RecName: Full=Cyclin-dependent kinase 12; AltName: Full=Cdc2-related kinase, arginine/serine-rich; Short=CrkRS; AltName: Full=Cell division cycle 2-related protein kinase 7; Short=CDC2-related protein kinase 7; AltName: Full=Cell division protein kinase 12; AltName: Full=Protein kinase for splicing component
gi|123780808|sp|Q3MJK5.1|CDK12_RAT

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