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Zcchc7 zinc finger, CCHC domain containing 7 [ Mus musculus (house mouse) ]

Gene ID: 319885, updated on 4-Jan-2025

Summary

Official Symbol
Zcchc7provided by MGI
Official Full Name
zinc finger, CCHC domain containing 7provided by MGI
Primary source
MGI:MGI:2442912
See related
Ensembl:ENSMUSG00000035649 AllianceGenome:MGI:2442912
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D4Wsu132e; 4930572I07Rik
Summary
Predicted to enable RNA binding activity. Predicted to be involved in nuclear RNA surveillance. Predicted to be located in cytosol and nucleolus. Predicted to be part of TRAMP complex. Is expressed in several structures, including central nervous system; dorsal root ganglion; extraembryonic component; sensory organ; and vibrissa. Orthologous to human ZCCHC7 (zinc finger CCHC-type containing 7). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Broad expression in bladder adult (RPKM 10.8), frontal lobe adult (RPKM 10.3) and 24 other tissues See more
Orthologs
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Genomic context

See Zcchc7 in Genome Data Viewer
Location:
4 B1; 4 23.57 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (44756556..44932215)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (44756558..44932215)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene paired box 5 Neighboring gene RIKEN cDNA 5730488B01 gene Neighboring gene Pax5 promoter region Neighboring gene Pax5 mhb enhancer Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:44769412-44769521 Neighboring gene aurora kinase C pseudogene Neighboring gene STARR-seq mESC enhancer starr_10082 Neighboring gene STARR-positive B cell enhancer mm9_chr4:44899270-44899570 Neighboring gene STARR-positive B cell enhancer mm9_chr4:44918473-44918774 Neighboring gene STARR-positive B cell enhancer ABC_E11237 Neighboring gene STARR-seq mESC enhancer starr_10084 Neighboring gene predicted gene 12678 Neighboring gene predicted gene, 30763

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

General gene information

Clone Names

  • MGC62855

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding  
enables molecular_function  
enables nucleic acid binding  
enables zinc ion binding  
Component Evidence Code Pubs
part_of TRAMP complex  
located_in cytosol  
located_in cytosol  
located_in nucleolus  
located_in nucleolus  

General protein information

Preferred Names
zinc finger CCHC domain-containing protein 7
Names
TRAMP-like complex RNA-binding factor ZCCHC7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_138590.4NP_613056.2  zinc finger CCHC domain-containing protein 7

    See identical proteins and their annotated locations for NP_613056.2

    Status: VALIDATED

    Source sequence(s)
    AA277854, AL805896, CF732773, CJ150974, CJ155194
    Consensus CDS
    CCDS18127.2
    UniProtKB/Swiss-Prot
    B1AX39, Q3TZN5, Q8C915, Q9CYZ9
    Related
    ENSMUSP00000103454.3, ENSMUST00000107824.9
    Conserved Domains (1) summary
    COG5082
    Location:233362
    AIR1; Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    44756556..44932215
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006537985.4XP_006538048.1  zinc finger CCHC domain-containing protein 7 isoform X2

    Conserved Domains (1) summary
    COG5082
    Location:233362
    AIR1; Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]
  2. XM_006537984.5XP_006538047.1  zinc finger CCHC domain-containing protein 7 isoform X1

    See identical proteins and their annotated locations for XP_006538047.1

    UniProtKB/Swiss-Prot
    B1AX39, Q3TZN5, Q8C915, Q9CYZ9
    Conserved Domains (1) summary
    COG5082
    Location:233362
    AIR1; Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]
  3. XM_006537986.4XP_006538049.1  zinc finger CCHC domain-containing protein 7 isoform X3

    Conserved Domains (1) summary
    COG5082
    Location:86215
    AIR1; Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]

RNA

  1. XR_004941921.1 RNA Sequence

  2. XR_003954962.2 RNA Sequence

  3. XR_003954965.2 RNA Sequence

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