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OR52R1 olfactory receptor family 52 subfamily R member 1 [ Homo sapiens (human) ]

Gene ID: 119695, updated on 4-Jan-2025

Summary

Official Symbol
OR52R1provided by HGNC
Official Full Name
olfactory receptor family 52 subfamily R member 1provided by HGNC
Primary source
HGNC:HGNC:15235
See related
Ensembl:ENSG00000279270 AllianceGenome:HGNC:15235
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR11-22
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jun 2015]
Annotation information
Note: Genetic polymorphisms result in both protein coding and non-coding alleles of this gene.
Orthologs
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Genomic context

See OR52R1 in Genome Data Viewer
Location:
11p15.4
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (4803433..4804380, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (4868927..4869874, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (4824663..4825610, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene matrix metallopeptidase 26 Neighboring gene olfactory receptor family 51 subfamily N member 1 pseudogene Neighboring gene olfactory receptor family 52 subfamily Y member 1 pseudogene Neighboring gene olfactory receptor family 51 subfamily F member 2 Neighboring gene olfactory receptor family 51 subfamily A member 8 pseudogene

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity  
enables olfactory receptor activity  
Component Evidence Code Pubs
is_active_in plasma membrane  

General protein information

Preferred Names
olfactory receptor 52R1
Names
olfactory receptor OR11-22

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005177.3NP_001005177.3  olfactory receptor 52R1

    Status: VALIDATED

    Source sequence(s)
    AC103710
    UniProtKB/Swiss-Prot
    Q6IFI0, Q8NGF1
    UniProtKB/TrEMBL
    A0A126GWP6
    Related
    ENSP00000485292.1, ENST00000624978.1
    Conserved Domains (2) summary
    pfam00001
    Location:44295
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:34311
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    4803433..4804380 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    4868927..4869874 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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