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Syf2 SYF2 pre-mRNA-splicing factor [ Rattus norvegicus (Norway rat) ]

Gene ID: 170933, updated on 4-Jan-2025

Summary

Official Symbol
Syf2provided by RGD
Official Full Name
SYF2 pre-mRNA-splicing factorprovided by RGD
Primary source
RGD:621592
See related
AllianceGenome:RGD:621592
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
P29; Gcipip
Summary
Involved in positive regulation of cell population proliferation. Predicted to be located in nuclear speck. Predicted to be part of Prp19 complex; U2-type catalytic step 2 spliceosome; and post-mRNA release spliceosomal complex. Biomarker of encephalitis. Orthologous to human SYF2 (SYF2 pre-mRNA splicing factor). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Kidney (RPKM 365.9), Lung (RPKM 352.1) and 9 other tissues See more
Orthologs
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Genomic context

See Syf2 in Genome Data Viewer
Location:
5q36
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (152440171..152448094)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (147156492..147164416)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (153269638..153277562)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 50A Neighboring gene arginine and serine rich protein 1 Neighboring gene uncharacterized LOC134479038 Neighboring gene uncharacterized LOC102551013

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

General gene information

Gene Ontology Provided by RGD

Component Evidence Code Pubs
part_of Prp19 complex  
part_of U2-type catalytic step 2 spliceosome  
part_of U2-type catalytic step 2 spliceosome  
part_of catalytic step 2 spliceosome  
part_of catalytic step 2 spliceosome  
located_in nuclear speck  
located_in nuclear speck  
located_in nucleus  
part_of post-mRNA release spliceosomal complex  

General protein information

Preferred Names
pre-mRNA-splicing factor SYF2
Names
GCIP-interacting protein p29
SYF2 homolog, RNA splicing factor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_133417.2NP_596908.2  pre-mRNA-splicing factor SYF2

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000005
    UniProtKB/Swiss-Prot
    Q4QRB2, Q91Y33
    Conserved Domains (1) summary
    pfam08231
    Location:89237
    SYF2; SYF2 splicing factor

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    152440171..152448094
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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