U.S. flag

An official website of the United States government

Art2b ADP-ribosyltransferase 2b [ Rattus norvegicus (Norway rat) ]

Gene ID: 293152, updated on 4-Jan-2025

Summary

Official Symbol
Art2bprovided by RGD
Official Full Name
ADP-ribosyltransferase 2bprovided by RGD
Primary source
RGD:3521
See related
EnsemblRapid:ENSRNOG00000019687 AllianceGenome:RGD:3521
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
LY2; Rt6; Ag-F; Art2; Ly-2; PtaA; ARTC2; Art2a; RT6.1; RT6.2
Summary
Predicted to enable NAD+-protein poly-ADP-ribosyltransferase activity; NAD+-protein-arginine ADP-ribosyltransferase activity; and hydrolase activity, acting on glycosyl bonds. Predicted to be involved in NAD catabolic process. Predicted to be located in external side of plasma membrane. [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Spleen (RPKM 89.3), Thymus (RPKM 44.3) and 2 other tissues See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Art2b in Genome Data Viewer
Location:
1q32
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (165368623..165386280, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (155956601..155974252, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (166665029..166685097, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120097347 Neighboring gene phosphodiesterase 2A Neighboring gene microRNA 139 Neighboring gene uncharacterized LOC120099897 Neighboring gene lactate dehydrogenase A, pseudogene 3 Neighboring gene ClpB family mitochondrial disaggregase

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Clone Names

  • MGC116041

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in NAD catabolic process  
Component Evidence Code Pubs
located_in external side of plasma membrane  
located_in plasma membrane  
located_in side of membrane  

General protein information

Preferred Names
T-cell ecto-ADP-ribosyltransferase 2
Names
ADP-ribosyltransferase 2
ADP-ribosyltransferase 2a
ADP-ribosyltransferase C2 and C3 toxin-like 2
Cell surface alloantigen peripheral T-cell antigen
NAD(+) glycohydrolase
T cell differentiation marker RT6.1
T-cell NAD(P)(+)--arginine ADP-ribosyltransferase 1
T-cell NAD(P)(+)--arginine ADP-ribosyltransferase 2
T-cell ecto-ADP-ribosyltransferase 1
T-cell mono(ADP-ribosyl)transferase 1
T-cell mono(ADP-ribosyl)transferase 2
T-cell surface protein Rt6.1
T-cell surface protein Rt6.2
alloantigen Rt6.1
alloantigen Rt6.2
cell surface alloantigen 6
mono(ADP-ribosyl)transferase 2A
mono(ADP-ribosyl)transferase 2B
NP_942030.1
XP_017444448.1
XP_038962041.1
XP_063141259.1
XP_063141264.1
XP_063141266.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_198735.3NP_942030.1  T-cell ecto-ADP-ribosyltransferase 2 precursor

    See identical proteins and their annotated locations for NP_942030.1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/Swiss-Prot
    P17982, P20974, P97912, Q4FZV8, Q95576, Q9EPH9
    UniProtKB/TrEMBL
    A6I6V2
    Related
    ENSRNOP00000069125.1, ENSRNOT00000087792.3
    Conserved Domains (1) summary
    pfam01129
    Location:27239
    ART; NAD:arginine ADP-ribosyltransferase

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    165368623..165386280 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063285189.1XP_063141259.1  T-cell ecto-ADP-ribosyltransferase 2 isoform X1

    UniProtKB/Swiss-Prot
    P17982
    UniProtKB/TrEMBL
    A0A0G2JUJ8
  2. XM_017588959.3XP_017444448.1  T-cell ecto-ADP-ribosyltransferase 2 isoform X2

    UniProtKB/Swiss-Prot
    P17982, P20974, P97912, Q4FZV8, Q95576, Q9EPH9
    UniProtKB/TrEMBL
    A6I6V2
    Conserved Domains (1) summary
    pfam01129
    Location:27239
    ART; NAD:arginine ADP-ribosyltransferase
  3. XM_039106113.2XP_038962041.1  T-cell ecto-ADP-ribosyltransferase 2 isoform X2

    UniProtKB/Swiss-Prot
    P17982, P20974, P97912, Q4FZV8, Q95576, Q9EPH9
    UniProtKB/TrEMBL
    A6I6V2
    Conserved Domains (1) summary
    pfam01129
    Location:27239
    ART; NAD:arginine ADP-ribosyltransferase
  4. XM_063285196.1XP_063141266.1  T-cell ecto-ADP-ribosyltransferase 2 isoform X2

    UniProtKB/Swiss-Prot
    P17982, P20974, P97912, Q4FZV8, Q95576, Q9EPH9
    UniProtKB/TrEMBL
    A6I6V2
  5. XM_063285194.1XP_063141264.1  T-cell ecto-ADP-ribosyltransferase 2 isoform X2

    UniProtKB/Swiss-Prot
    P17982, P20974, P97912, Q4FZV8, Q95576, Q9EPH9
    UniProtKB/TrEMBL
    A6I6V2
External link. Please review our privacy policy.