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Zrsr2-ps1 zinc finger (CCCH type), RNA binding motif and serine/arginine rich 2, pseudogene 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 498425, updated on 4-Jan-2025

Summary

Official Symbol
Zrsr2-ps1provided by RGD
Official Full Name
zinc finger (CCCH type), RNA binding motif and serine/arginine rich 2, pseudogene 1provided by RGD
Primary source
RGD:1561824
See related
AllianceGenome:RGD:1561824
Gene type
pseudo
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Zrsr1
Summary
Predicted to enable pre-mRNA 3'-splice site binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of U12-type spliceosomal complex and U2AF complex. Human ortholog(s) of this gene implicated in acute myeloid leukemia and myelodysplastic syndrome. Orthologous to human ZRSR2P1 (ZRSR2 pseudogene 1) and ZRSR2 (zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Brain (RPKM 131.4), Heart (RPKM 111.8) and 9 other tissues See more
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Genomic context

See Zrsr2-ps1 in Genome Data Viewer
Location:
14q22
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (101173861..101179999)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (96972651..96978364)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (107750162..107751895)

Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102552414 Neighboring gene copper metabolism domain containing 1 Neighboring gene uncharacterized LOC134481876 Neighboring gene uncharacterized LOC134481877 Neighboring gene uncharacterized LOC120096694 Neighboring gene chaperonin containing TCP1 subunit 4 Neighboring gene FAM161 centrosomal protein A

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Other Names

  • U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1
  • zinc finger (CCCH type), RNA binding motif and serine/arginine rich 1

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables metal ion binding  
enables pre-mRNA 3'-splice site binding  
Component Evidence Code Pubs
part_of U12-type spliceosomal complex  
part_of U2AF complex  
part_of spliceosomal complex  
part_of spliceosomal complex  

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086032.1 Reference GRCr8

    Range
    101173861..101179999
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_010057752.1 RNA Sequence

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