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Fau FAU ubiquitin like and ribosomal protein S30 fusion [ Mus musculus (house mouse) ]

Gene ID: 14109, updated on 4-Jan-2025

Summary

Official Symbol
Fauprovided by MGI
Official Full Name
FAU ubiquitin like and ribosomal protein S30 fusionprovided by MGI
Primary source
MGI:MGI:102547
See related
Ensembl:ENSMUSG00000038274 AllianceGenome:MGI:102547
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MNSFB; MNSFbeta
Summary
A structural constituent of ribosome. Involved in antimicrobial humoral immune response mediated by antimicrobial peptide and defense response to Gram-positive bacterium. Part of cytosolic small ribosomal subunit. Is expressed in decidua; embryo; and uterus. Orthologous to human FAU (FAU ubiquitin like and ribosomal protein S30 fusion). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Ubiquitous expression in spleen adult (RPKM 573.2), ovary adult (RPKM 507.1) and 28 other tissues See more
Orthologs
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Genomic context

See Fau in Genome Data Viewer
Location:
19 A; 19 4.34 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (6107977..6109554)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (6057947..6059524)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene synovial apoptosis inhibitor 1, synoviolin Neighboring gene microRNA 6988 Neighboring gene mitochondrial ribosomal protein L49 Neighboring gene STARR-seq mESC enhancer starr_45418 Neighboring gene zinc finger, HIT domain containing 2 Neighboring gene transmembrane 7 superfamily member 2 Neighboring gene VPS51 GARP complex subunit

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding PubMed 
enables protein tag activity  
enables structural constituent of ribosome PubMed 
enables structural constituent of ribosome  
enables ubiquitin protein ligase binding  
Component Evidence Code Pubs
is_active_in cytoplasm  
located_in cytoplasm PubMed 
located_in cytosolic ribosome  
part_of cytosolic small ribosomal subunit PubMed 
part_of cytosolic small ribosomal subunit  
part_of cytosolic small ribosomal subunit PubMed 
located_in extracellular space  
located_in extracellular space  
is_active_in nucleus  
located_in nucleus  
located_in nucleus  

General protein information

Preferred Names
ubiquitin-like FUBI-ribosomal protein eS30 fusion protein
Names
40S ribosomal protein S30
FAU ubiquitin-like and ribosomal protein S30
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)
MNSF-beta
monoclonal non-specific suppressor factor beta
monoclonal nonspecific suppressor factor beta
monoclonal nonspecific suppressor factor betamonoclonal nonspecific suppressor factor beta
ubiquitin-like protein FUBI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001160239.3NP_001153711.1  ubiquitin-like FUBI-ribosomal protein eS30 fusion protein

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 3. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    AC131692
    Consensus CDS
    CCDS29489.1
    UniProtKB/Swiss-Prot
    P35545, P62862, Q642K5, Q9JJ24
    UniProtKB/TrEMBL
    Q3THB2
    Related
    ENSMUSP00000042835.6, ENSMUST00000043074.14
    Conserved Domains (2) summary
    cd01793
    Location:174
    Ubl_FUBI; ubiquitin-like (Ubl) domain found in ubiquitin-like protein FUBI and similar proteins
    pfam04758
    Location:75132
    Ribosomal_S30; Ribosomal protein S30
  2. NM_001190436.2NP_001177365.1  ubiquitin-like FUBI-ribosomal protein eS30 fusion protein

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) represents the longest transcript. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    AC131692
    Consensus CDS
    CCDS29489.1
    UniProtKB/Swiss-Prot
    P35545, P62862, Q642K5, Q9JJ24
    UniProtKB/TrEMBL
    Q3THB2
    Related
    ENSMUSP00000136358.2, ENSMUST00000179142.2
    Conserved Domains (2) summary
    cd01793
    Location:174
    Ubl_FUBI; ubiquitin-like (Ubl) domain found in ubiquitin-like protein FUBI and similar proteins
    pfam04758
    Location:75132
    Ribosomal_S30; Ribosomal protein S30
  3. NM_007990.4NP_032016.1  ubiquitin-like FUBI-ribosomal protein eS30 fusion protein

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) differs in the 5' UTR, compared to variant 3. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    AC131692
    Consensus CDS
    CCDS29489.1
    UniProtKB/Swiss-Prot
    P35545, P62862, Q642K5, Q9JJ24
    UniProtKB/TrEMBL
    Q3THB2
    Related
    ENSMUSP00000136803.2, ENSMUST00000178310.9
    Conserved Domains (2) summary
    cd01793
    Location:174
    Ubl_FUBI; ubiquitin-like (Ubl) domain found in ubiquitin-like protein FUBI and similar proteins
    pfam04758
    Location:75132
    Ribosomal_S30; Ribosomal protein S30

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    6107977..6109554
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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