U.S. flag

An official website of the United States government

ZNF599 zinc finger protein 599 [ Homo sapiens (human) ]

Gene ID: 148103, updated on 4-Jan-2025

Summary

Official Symbol
ZNF599provided by HGNC
Official Full Name
zinc finger protein 599provided by HGNC
Primary source
HGNC:HGNC:26408
See related
Ensembl:ENSG00000153896 AllianceGenome:HGNC:26408
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jan 2025]
Expression
Broad expression in testis (RPKM 1.7), ovary (RPKM 1.1) and 24 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See ZNF599 in Genome Data Viewer
Location:
19q13.11
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (34758073..34807601, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (37302660..37351996, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (35248978..35264120, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10507 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10508 Neighboring gene zinc finger protein 181 Neighboring gene uncharacterized LOC124904698 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10509 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14452 Neighboring gene uncharacterized LOC124904696 Neighboring gene zinc finger protein 134 pseudogene Neighboring gene long intergenic non-protein coding RNA 1801 Neighboring gene zinc finger protein 396 pseudogene Neighboring gene long intergenic non-protein coding RNA 2965 Neighboring gene long intergenic non-protein coding RNA 3049

Genomic regions, transcripts, and products

Expression

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Interactions

General gene information

Clone Names

  • FLJ50920

Gene Ontology Provided by GOA

Component Evidence Code Pubs
is_active_in nucleus  

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007248.3NP_001007249.1  zinc finger protein 599

    See identical proteins and their annotated locations for NP_001007249.1

    Status: VALIDATED

    Source sequence(s)
    AC020910, AK055225
    Consensus CDS
    CCDS32991.1
    UniProtKB/Swiss-Prot
    Q569K0, Q5PRG1, Q96NL3
    Related
    ENSP00000333802.6, ENST00000329285.13
    Conserved Domains (5) summary
    smart00349
    Location:969
    KRAB; krueppel associated box
    COG5048
    Location:253580
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:369389
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:948
    KRAB; KRAB box
    pfam13465
    Location:549574
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    34758073..34807601 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047438256.1XP_047294212.1  zinc finger protein 599 isoform X1

  2. XM_047438255.1XP_047294211.1  zinc finger protein 599 isoform X1

  3. XM_047438254.1XP_047294210.1  zinc finger protein 599 isoform X1

  4. XM_047438257.1XP_047294213.1  zinc finger protein 599 isoform X1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    37302660..37351996 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054319964.1XP_054175939.1  zinc finger protein 599 isoform X1

  2. XM_054319965.1XP_054175940.1  zinc finger protein 599 isoform X1

  3. XM_054319966.1XP_054175941.1  zinc finger protein 599 isoform X1

  4. XM_054319967.1XP_054175942.1  zinc finger protein 599 isoform X1

External link. Please review our privacy policy.