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    Stmn3 stathmin 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 29246, updated on 4-Jan-2025

    Summary

    Official Symbol
    Stmn3provided by RGD
    Official Full Name
    stathmin 3provided by RGD
    Primary source
    RGD:3628
    See related
    EnsemblRapid:ENSRNOG00000013657 AllianceGenome:RGD:3628
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Sclip
    Summary
    Enables protein-folding chaperone binding activity. Involved in cellular response to nerve growth factor stimulus. Located in cytosol and perinuclear region of cytoplasm. Orthologous to human STMN3 (stathmin 3). [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Restricted expression toward (RPKM 1907.3) See more
    Orthologs
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    Genomic context

    See Stmn3 in Genome Data Viewer
    Location:
    3q43
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (188794358..188802494, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (168416810..168424946, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (176808016..176816108, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene helicase with zinc finger 2 Neighboring gene uncharacterized LOC120101833 Neighboring gene glucocorticoid modulatory element binding protein 2 Neighboring gene regulator of telomere elongation helicase 1 Neighboring gene ARF related protein 1 Neighboring gene zinc finger CCCH-type and G-patch domain containing Neighboring gene Lck interacting transmembrane adaptor 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables protein binding PubMed 
    enables protein domain specific binding  
    enables protein domain specific binding  
    enables protein-folding chaperone binding PubMed 
    enables tubulin binding  
    enables tubulin binding PubMed 
    Process Evidence Code Pubs
    involved_in blastocyst hatching  
    acts_upstream_of_or_within blastocyst hatching  
    involved_in cellular response to nerve growth factor stimulus PubMed 
    involved_in cytoplasmic microtubule organization  
    involved_in cytoplasmic microtubule organization  
    involved_in cytoplasmic microtubule organization PubMed 
    involved_in microtubule depolymerization  
    involved_in negative regulation of Rac protein signal transduction  
    involved_in negative regulation of Rac protein signal transduction  
    involved_in negative regulation of Rac protein signal transduction PubMed 
    involved_in neuron projection development  
    involved_in neuron projection development  
    involved_in neuron projection development  
    involved_in neuron projection development PubMed 
    involved_in regulation of cytoskeleton organization  
    involved_in regulation of cytoskeleton organization PubMed 
    involved_in regulation of microtubule polymerization or depolymerization  
    involved_in regulation of microtubule polymerization or depolymerization  
    Component Evidence Code Pubs
    located_in Golgi apparatus  
    located_in Golgi apparatus  
    is_active_in cytoplasm  
    located_in cytoplasm  
    located_in cytoplasm PubMed 
    located_in cytosol PubMed 
    located_in cytosol  
    located_in cytosol  
    located_in growth cone  
    is_active_in neuron projection  
    located_in perinuclear region of cytoplasm PubMed 

    General protein information

    Preferred Names
    stathmin-3
    Names
    SCG10-like protein
    scgn10 like-protein
    stathmin-like 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001395145.1NP_001382074.1  stathmin-3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/Swiss-Prot
      Q9JHU6
      UniProtKB/TrEMBL
      A6KM20, D3ZI49
      Related
      ENSRNOP00000089824.1, ENSRNOT00000109405.2
      Conserved Domains (1) summary
      pfam00836
      Location:39175
      Stathmin; Stathmin family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      188794358..188802494 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063283198.1XP_063139268.1  stathmin-3 isoform X1

      UniProtKB/Swiss-Prot
      Q9JHU6
      UniProtKB/TrEMBL
      A0A0G2K8P5, A6KM21
      Related
      ENSRNOP00000018697.5, ENSRNOT00000018697.8

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