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Tfip11 tuftelin interacting protein 11 [ Rattus norvegicus (Norway rat) ]

Gene ID: 288718, updated on 4-Jan-2025

Summary

Official Symbol
Tfip11provided by RGD
Official Full Name
tuftelin interacting protein 11provided by RGD
Primary source
RGD:1311449
See related
EnsemblRapid:ENSRNOG00000000663 AllianceGenome:RGD:1311449
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable nucleic acid binding activity. Predicted to be involved in negative regulation of protein-containing complex assembly and spliceosomal complex disassembly. Predicted to be located in chromosome, telomeric region; extracellular matrix; and nuclear lumen. Predicted to be part of U2-type post-mRNA release spliceosomal complex and catalytic step 2 spliceosome. Orthologous to human TFIP11 (tuftelin interacting protein 11). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Kidney (RPKM 65.5), Thymus (RPKM 64.2) and 9 other tissues See more
Orthologs
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Genomic context

See Tfip11 in Genome Data Viewer
Location:
12q16
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (49960025..49972257, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (44299619..44311851, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (50320820..50333052, complement)

Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene aspartate beta-hydroxylase domain containing 2 Neighboring gene coiled-coil domain-containing protein 121-like Neighboring gene HPS4, biogenesis of lysosomal organelles complex 3 subunit 2 Neighboring gene SRR1 domain containing Neighboring gene tyrosylprotein sulfotransferase 2 Neighboring gene crystallin, beta B1 Neighboring gene crystallin, beta A4

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables nucleic acid binding  
Component Evidence Code Pubs
part_of U2-type post-mRNA release spliceosomal complex  
part_of U2-type post-mRNA release spliceosomal complex  
part_of U2-type post-mRNA release spliceosomal complex  
part_of catalytic step 2 spliceosome  
located_in chromosome, telomeric region  
located_in cytoplasm  
located_in extracellular matrix  
located_in nuclear speck  
located_in nuclear speck  
located_in nucleolus  
part_of spliceosomal complex  
part_of spliceosomal complex  
part_of spliceosomal complex  

General protein information

Preferred Names
tuftelin-interacting protein 11
Names
STIP-1
septin and tuftelin-interacting protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008291.1NP_001008292.1  tuftelin-interacting protein 11

    See identical proteins and their annotated locations for NP_001008292.1

    Status: PROVISIONAL

    Source sequence(s)
    BC085809
    UniProtKB/Swiss-Prot
    Q5U2Y6
    UniProtKB/TrEMBL
    A0A8I6A3N9, A6J264
    Related
    ENSRNOP00000000828.3, ENSRNOT00000000828.6
    Conserved Domains (3) summary
    pfam01585
    Location:149193
    G-patch; G-patch domain
    pfam07842
    Location:397666
    GCFC; GC-rich sequence DNA-binding factor-like protein
    pfam12457
    Location:18104
    TIP_N; Tuftelin interacting protein N terminal

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086030.1 Reference GRCr8

    Range
    49960025..49972257 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063271216.1XP_063127286.1  tuftelin-interacting protein 11 isoform X1

    UniProtKB/Swiss-Prot
    Q5U2Y6
    UniProtKB/TrEMBL
    A0A8I6A3N9, A6J264
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