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Mrps11 mitochondrial ribosomal protein S11 [ Mus musculus (house mouse) ]

Gene ID: 67994, updated on 4-Jan-2025

Summary

Official Symbol
Mrps11provided by MGI
Official Full Name
mitochondrial ribosomal protein S11provided by MGI
Primary source
MGI:MGI:1915244
See related
Ensembl:ENSMUSG00000030611 AllianceGenome:MGI:1915244
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
S11mt; MRP-S11; 0710005I03Rik
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Located in mitochondrion. Is expressed in several structures, including early conceptus; gonad; heart; liver; and metanephros. Orthologous to human MRPS11 (mitochondrial ribosomal protein S11). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Ubiquitous expression in ovary adult (RPKM 23.6), liver E14.5 (RPKM 18.9) and 28 other tissues See more
Orthologs
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Genomic context

See Mrps11 in Genome Data Viewer
Location:
7 D2; 7 44.8 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (78432879..78442736)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (78783131..78792988)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 30892 Neighboring gene STARR-positive B cell enhancer mm9_chr7:85927896-85928197 Neighboring gene mitochondrial ribosomal protein L46 Neighboring gene DET1 partner of COP1 E3 ubiquitin ligase Neighboring gene STARR-seq mESC enhancer starr_19254 Neighboring gene STARR-seq mESC enhancer starr_19255 Neighboring gene predicted gene, 57212 Neighboring gene microRNA 7-2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Interactions

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables structural constituent of ribosome  
enables structural constituent of ribosome PubMed 
Process Evidence Code Pubs
involved_in mitochondrial translation PubMed 
involved_in mitochondrial translation PubMed 
involved_in translation  
Component Evidence Code Pubs
located_in mitochondrial inner membrane PubMed 
part_of mitochondrial small ribosomal subunit  
part_of mitochondrial small ribosomal subunit PubMed 
part_of mitochondrial small ribosomal subunit PubMed 
part_of mitochondrial small ribosomal subunit PubMed 
located_in mitochondrion PubMed 
located_in mitochondrion  

General protein information

Preferred Names
small ribosomal subunit protein uS11m
Names
28S ribosomal protein S11, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001360702.1NP_001347631.1  small ribosomal subunit protein uS11m isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1.
    Source sequence(s)
    AC156556, AK160207
    Conserved Domains (1) summary
    cl00332
    Location:8116
    Ribosomal_S11; Ribosomal protein S11
  2. NM_026498.2NP_080774.2  small ribosomal subunit protein uS11m isoform 1

    See identical proteins and their annotated locations for NP_080774.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AK152027, BB840699
    Consensus CDS
    CCDS21374.1
    UniProtKB/Swiss-Prot
    Q99JT7, Q99N86, Q9DCA2
    UniProtKB/TrEMBL
    Q3TLY7, Q3U8Y1
    Related
    ENSMUSP00000032840.5, ENSMUST00000032840.5
    Conserved Domains (1) summary
    cl00332
    Location:82190
    Ribosomal_S11; Ribosomal protein S11

RNA

  1. NR_153793.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate splice junction compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC156556

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    78432879..78442736
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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