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OMD osteomodulin [ Homo sapiens (human) ]

Gene ID: 4958, updated on 4-Jan-2025

Summary

Official Symbol
OMDprovided by HGNC
Official Full Name
osteomodulinprovided by HGNC
Primary source
HGNC:HGNC:8134
See related
Ensembl:ENSG00000127083 MIM:618926; AllianceGenome:HGNC:8134
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OSAD; SLRR2C
Summary
Predicted to be involved in cell adhesion. Located in extracellular exosome. [provided by Alliance of Genome Resources, Jan 2025]
Expression
Broad expression in heart (RPKM 10.0), fat (RPKM 8.3) and 20 other tissues See more
Orthologs
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Genomic context

See OMD in Genome Data Viewer
Location:
9q22.31
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (92412380..92424471, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (104578877..104590965, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (95174662..95186753, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene phagophore assembly factor 1 pseudogene Neighboring gene centromere protein P Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_109628 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_109638 Neighboring gene osteoglycin Neighboring gene asporin Neighboring gene extracellular matrix protein 2 Neighboring gene microRNA 4670

Genomic regions, transcripts, and products

Expression

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

General gene information

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in cell adhesion  
Component Evidence Code Pubs
located_in Golgi lumen  
located_in extracellular exosome PubMed 
located_in extracellular matrix  
located_in extracellular region  
is_active_in extracellular space  
located_in lysosomal lumen  

General protein information

Preferred Names
osteomodulin
Names
KSPG osteomodulin
keratan sulfate proteoglycan osteomodulin
osteoadherin proteoglycan

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_005014.3NP_005005.1  osteomodulin precursor

    See identical proteins and their annotated locations for NP_005005.1

    Status: VALIDATED

    Source sequence(s)
    AL137848
    Consensus CDS
    CCDS6696.1
    UniProtKB/Swiss-Prot
    Q5TBF4, Q99983
    UniProtKB/TrEMBL
    B2R7N9
    Related
    ENSP00000364700.4, ENST00000375550.5
    Conserved Domains (2) summary
    sd00033
    Location:94116
    LRR_RI; leucine-rich repeat [structural motif]
    cl26018
    Location:68305
    NEL; C-terminal novel E3 ligase, LRR-interacting

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    92412380..92424471 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_025791788.1 Reference GRCh38.p14 PATCHES

    Range
    247109..259200 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    104578877..104590965 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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