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    Slc2a10 solute carrier family 2 (facilitated glucose transporter), member 10 [ Mus musculus (house mouse) ]

    Gene ID: 170441, updated on 13-Jan-2025

    Summary

    Official Symbol
    Slc2a10provided by MGI
    Official Full Name
    solute carrier family 2 (facilitated glucose transporter), member 10provided by MGI
    Primary source
    MGI:MGI:2156687
    See related
    Ensembl:ENSMUSG00000027661 AllianceGenome:MGI:2156687
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Glut10
    Summary
    This gene encodes a class III facilitative glucose transporter. Mutations in the related gene in human are associated with arterial tortuosity syndrome. [provided by RefSeq, Dec 2013]
    Expression
    Biased expression in stomach adult (RPKM 17.5), colon adult (RPKM 9.3) and 13 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Slc2a10 in Genome Data Viewer
    Location:
    2 H3; 2 85.66 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (165345817..165361837)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (165503897..165519917)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 Neighboring gene origin of replication near adenosine deaminase Neighboring gene predicted gene 14437 Neighboring gene transformation related protein 53 regulating kinase A Neighboring gene EYA transcriptional coactivator and phosphatase 2 Neighboring gene predicted gene, 29993 Neighboring gene STARR-seq mESC enhancer starr_06353 Neighboring gene STARR-positive B cell enhancer ABC_E4519 Neighboring gene STARR-seq mESC enhancer starr_06355 Neighboring gene zinc finger, MYND-type containing 8 Neighboring gene STARR-seq mESC enhancer starr_06364 Neighboring gene predicted gene 11465

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Gene Ontology Provided by MGI

    Items 1 - 25 of 32
    Process Evidence Code Pubs
    involved_in D-glucose import across plasma membrane  
    involved_in D-glucose import across plasma membrane  
    involved_in D-glucose transmembrane transport  
    acts_upstream_of_or_within D-glucose transmembrane transport PubMed 
    involved_in artery development  
    acts_upstream_of_or_within artery development  
    involved_in cell redox homeostasis  
    acts_upstream_of_or_within cell redox homeostasis  
    involved_in circulatory system development  
    involved_in dehydroascorbic acid transport  
    involved_in dehydroascorbic acid transport  
    involved_in embryonic skeletal joint development  
    acts_upstream_of_or_within embryonic skeletal joint development  
    involved_in negative regulation of connective tissue growth factor production  
    acts_upstream_of_or_within negative regulation of connective tissue growth factor production  
    acts_upstream_of_or_within negative regulation of gene expression  
    involved_in negative regulation of integrin-mediated signaling pathway  
    acts_upstream_of negative regulation of integrin-mediated signaling pathway  
    involved_in negative regulation of proteoglycan biosynthetic process  
    acts_upstream_of_or_within negative regulation of proteoglycan biosynthetic process  
    involved_in negative regulation of transforming growth factor beta receptor signaling pathway  
    acts_upstream_of_or_within negative regulation of transforming growth factor beta receptor signaling pathway  
    involved_in positive regulation of gene expression  
    acts_upstream_of_or_within positive regulation of gene expression  
    involved_in positive regulation of proteoglycan biosynthetic process  
    acts_upstream_of_or_within positive regulation of proteoglycan biosynthetic process  
    involved_in positive regulation of transforming growth factor beta receptor signaling pathway  
    acts_upstream_of_or_within positive regulation of transforming growth factor beta receptor signaling pathway  
    involved_in regulation of extracellular matrix organization  
    acts_upstream_of_or_within regulation of extracellular matrix organization  
    involved_in skin development  
    acts_upstream_of_or_within skin development  
    Items 1 - 25 of 32
    Component Evidence Code Pubs
    located_in cytosol  
    located_in cytosol  
    located_in endomembrane system  
    is_active_in membrane  
    located_in perinuclear region of cytoplasm  
    located_in perinuclear region of cytoplasm  
    is_active_in plasma membrane  
    located_in plasma membrane PubMed 

    General protein information

    Preferred Names
    solute carrier family 2, facilitated glucose transporter member 10
    Names
    glucose transporter type 10

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_130451.3NP_569718.1  solute carrier family 2, facilitated glucose transporter member 10

      See identical proteins and their annotated locations for NP_569718.1

      Status: REVIEWED

      Source sequence(s)
      AK052156, BB732254, BY230011
      Consensus CDS
      CCDS17083.1
      UniProtKB/Swiss-Prot
      Q8VHD6
      UniProtKB/TrEMBL
      A2A4V1
      Related
      ENSMUSP00000029196.5, ENSMUST00000029196.5
      Conserved Domains (2) summary
      cd06174
      Location:14323
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      pfam00083
      Location:11508
      Sugar_tr; Sugar (and other) transporter

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      165345817..165361837
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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