U.S. flag

An official website of the United States government

Atf2 activating transcription factor 2 [ Mus musculus (house mouse) ]

Gene ID: 11909, updated on 4-Jan-2025

Summary

Official Symbol
Atf2provided by MGI
Official Full Name
activating transcription factor 2provided by MGI
Primary source
MGI:MGI:109349
See related
Ensembl:ENSMUSG00000027104 AllianceGenome:MGI:109349
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mXBP; Atf-2; Creb2; CRE-BP; D130078H02Rik; Tg(Gzma-Klra1)7Wum
Summary
Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; cAMP response element binding activity; and protein dimerization activity. Involved in several processes, including growth plate cartilage development; hindbrain development; and intracellular signal transduction. Acts upstream of or within with a positive effect on cellular response to leucine starvation and regulation of transcription by RNA polymerase II. Acts upstream of or within adipose tissue development; outflow tract morphogenesis; and positive regulation of transforming growth factor beta2 production. Located in membrane; nucleus; and site of double-strand break. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and limb. Used to study meconium aspiration syndrome and osteochondrodysplasia. Orthologous to human ATF2 (activating transcription factor 2). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Ubiquitous expression in CNS E14 (RPKM 7.9), frontal lobe adult (RPKM 7.8) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Atf2 in Genome Data Viewer
Location:
2 C3; 2 43.86 cM
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (73646853..73723094, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (73816509..73892677, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 53265 Neighboring gene chimerin 1, opposite strand 3 Neighboring gene chimerin 1 Neighboring gene STARR-seq mESC enhancer starr_04840 Neighboring gene STARR-seq mESC enhancer starr_04842 Neighboring gene STARR-seq mESC enhancer starr_04843 Neighboring gene STARR-positive B cell enhancer mm9_chr2:73705882-73706183 Neighboring gene STARR-positive B cell enhancer ABC_E809 Neighboring gene STARR-positive B cell enhancer ABC_E4468 Neighboring gene predicted gene 10822 Neighboring gene ATP synthase membrane subunit c locus 3 Neighboring gene predicted gene, 39851

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

General gene information

Clone Names

  • MGC105211, MGC105222

Gene Ontology Provided by MGI

Items 1 - 25 of 35
Function Evidence Code Pubs
enables DNA binding PubMed 
enables DNA-binding transcription activator activity, RNA polymerase II-specific PubMed 
enables DNA-binding transcription activator activity, RNA polymerase II-specific  
enables DNA-binding transcription factor activity PubMed 
enables DNA-binding transcription factor activity, RNA polymerase II-specific  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding  
enables RNA polymerase II-specific DNA-binding transcription factor binding  
enables RNA polymerase II-specific DNA-binding transcription factor binding  
enables cAMP response element binding  
enables cAMP response element binding PubMed 
enables cAMP response element binding  
enables cAMP response element binding protein binding  
enables cAMP response element binding protein binding  
enables chromatin binding PubMed 
enables cis-regulatory region sequence-specific DNA binding  
enables histone H2B acetyltransferase activity  
enables histone H2B acetyltransferase activity  
enables histone H4 acetyltransferase activity  
enables histone H4 acetyltransferase activity  
enables identical protein binding  
enables leucine zipper domain binding PubMed 
enables metal ion binding  
enables promoter-specific chromatin binding PubMed 
enables promoter-specific chromatin binding PubMed 
enables protein binding PubMed 
enables protein heterodimerization activity PubMed 
enables protein homodimerization activity PubMed 
enables protein kinase binding  
enables protein kinase binding  
enables protein-containing complex binding  
enables sequence-specific DNA binding PubMed 
enables sequence-specific DNA binding  
enables sequence-specific double-stranded DNA binding  
Items 1 - 25 of 35
Items 1 - 25 of 76
Process Evidence Code Pubs
involved_in BMP signaling pathway PubMed 
involved_in DNA damage response PubMed 
involved_in DNA damage response  
involved_in DNA damage response  
involved_in JNK cascade PubMed 
involved_in MAPK cascade PubMed 
involved_in NK T cell differentiation PubMed 
involved_in abducens nucleus development PubMed 
acts_upstream_of_or_within adipose tissue development PubMed 
involved_in amelogenesis  
involved_in apoptotic process PubMed 
involved_in apoptotic process involved in development PubMed 
involved_in brainstem development PubMed 
involved_in cellular response to anisomycin PubMed 
involved_in cellular response to anisomycin PubMed 
acts_upstream_of_or_within_positive_effect cellular response to leucine starvation PubMed 
involved_in cellular response to oxidative stress PubMed 
involved_in cellular response to virus PubMed 
involved_in detection of cell density PubMed 
involved_in facial nucleus development PubMed 
involved_in gene expression PubMed 
involved_in gene expression PubMed 
involved_in growth plate cartilage chondrocyte differentiation PubMed 
involved_in growth plate cartilage chondrocyte proliferation PubMed 
involved_in heart development PubMed 
involved_in hematopoietic progenitor cell differentiation PubMed 
involved_in hepatocyte apoptotic process PubMed 
involved_in hypoglossal nucleus development PubMed 
involved_in in utero embryonic development PubMed 
involved_in in utero embryonic development PubMed 
involved_in intrinsic apoptotic signaling pathway in response to hypoxia PubMed 
involved_in lipid metabolic process PubMed 
involved_in liver development PubMed 
involved_in mRNA transcription by RNA polymerase II PubMed 
involved_in mitotic intra-S DNA damage checkpoint signaling  
involved_in mitotic intra-S DNA damage checkpoint signaling  
involved_in motor neuron apoptotic process PubMed 
involved_in negative regulation of angiogenesis  
involved_in negative regulation of angiogenesis  
involved_in negative regulation of epithelial cell proliferation  
involved_in negative regulation of transcription by RNA polymerase II  
involved_in neurofilament cytoskeleton organization PubMed 
acts_upstream_of_or_within outflow tract morphogenesis PubMed 
involved_in p38MAPK cascade PubMed 
involved_in p38MAPK cascade PubMed 
involved_in positive regulation of DNA-binding transcription factor activity  
involved_in positive regulation of DNA-binding transcription factor activity  
involved_in positive regulation of cardiac muscle myoblast proliferation  
involved_in positive regulation of cardiac muscle myoblast proliferation  
involved_in positive regulation of gene expression  
involved_in positive regulation of mitochondrial membrane permeability involved in apoptotic process  
involved_in positive regulation of mitochondrial membrane permeability involved in apoptotic process  
involved_in positive regulation of neuron apoptotic process  
involved_in positive regulation of protein phosphorylation PubMed 
involved_in positive regulation of transcription by RNA polymerase II PubMed 
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II PubMed 
involved_in positive regulation of transcription by RNA polymerase II PubMed 
acts_upstream_of_or_within_positive_effect positive regulation of transcription by RNA polymerase II PubMed 
involved_in positive regulation of transcription by RNA polymerase II  
acts_upstream_of_or_within positive regulation of transforming growth factor beta2 production PubMed 
involved_in protein import into nucleus PubMed 
involved_in regulation of DNA-templated transcription  
involved_in regulation of DNA-templated transcription  
involved_in regulation of cell cycle checkpoint PubMed 
involved_in regulation of transcription by RNA polymerase II  
acts_upstream_of_or_within_positive_effect regulation of transcription by RNA polymerase II PubMed 
involved_in regulation of transcription by RNA polymerase II  
involved_in response to organic cyclic compound PubMed 
involved_in response to osmotic stress  
involved_in response to osmotic stress  
involved_in transcription initiation-coupled chromatin remodeling  
involved_in transcription initiation-coupled chromatin remodeling  
involved_in vacuole organization PubMed 
acts_upstream_of_or_within white fat cell differentiation PubMed 
involved_in white fat cell differentiation PubMed 
involved_in white fat cell differentiation PubMed 
Items 1 - 25 of 76
Component Evidence Code Pubs
part_of CCAAT-binding factor complex PubMed 
part_of H4 histone acetyltransferase complex  
part_of H4 histone acetyltransferase complex  
part_of RNA polymerase II transcription regulator complex  
located_in chromatin  
located_in cytoplasm  
located_in cytoplasm  
located_in membrane PubMed 
located_in mitochondrial outer membrane  
located_in mitochondrial outer membrane  
located_in nucleoplasm  
located_in nucleoplasm  
located_in nucleus PubMed 
located_in nucleus PubMed 
located_in site of double-strand break PubMed 
located_in site of double-strand break  
located_in site of double-strand break  

General protein information

Preferred Names
cyclic AMP-dependent transcription factor ATF-2
Names
cAMP response element-binding protein CRE-BP1
cAMP-dependent transcription factor ATF-2
NP_001020264.1
NP_001271298.1
NP_001271299.1
NP_001271300.1
NP_001271301.1
NP_001271302.1
NP_001271303.1
NP_001271305.1
NP_033845.1
XP_030102700.1
XP_030102701.1
XP_030102703.1
XP_030102704.1
XP_030102706.1
XP_030102707.1
XP_030102710.1
XP_030102713.1
XP_030102715.1
XP_030102718.1
XP_030102727.1
XP_030102732.1
XP_030102733.1
XP_036013584.1
XP_036013587.1
XP_036013593.1
XP_036013600.1
XP_036013601.1
XP_036013602.1
XP_036013604.1
XP_036013605.1
XP_036013606.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025093.2NP_001020264.1  cyclic AMP-dependent transcription factor ATF-2 isoform 1

    See identical proteins and their annotated locations for NP_001020264.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest protein (isoform 1).
    Source sequence(s)
    AK051591, AL844581, AL845523, BC079883, BC082596
    Consensus CDS
    CCDS16134.1
    UniProtKB/Swiss-Prot
    P16951, Q64089, Q64090, Q64091
    UniProtKB/TrEMBL
    Q8CGB4
    Conserved Domains (4) summary
    cd12192
    Location:4784
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    PRK14951
    Location:184312
    PRK14951; DNA polymerase III subunits gamma and tau; Provisional
    cd14687
    Location:336396
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
    sd00019
    Location:931
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. NM_001284369.1NP_001271298.1  cyclic AMP-dependent transcription factor ATF-2 isoform 2

    See identical proteins and their annotated locations for NP_001271298.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, lacks an alternate in-frame exon in the 5' coding region and uses a downstream start codon compared to variant 1. The resulting protein (isoform 2) is shorter compared to isoform 1. Variants 2 and 3 encode the same protein.
    Source sequence(s)
    AK035438, AK139515, AL844581, AL845523
    Consensus CDS
    CCDS16135.1
    UniProtKB/TrEMBL
    Q543G2, Q68FE3
    Related
    ENSMUSP00000107641.3, ENSMUST00000112010.9
    Conserved Domains (3) summary
    cd12192
    Location:944
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    PRK14951
    Location:144272
    PRK14951; DNA polymerase III subunits gamma and tau; Provisional
    cd14687
    Location:296356
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
  3. NM_001284370.1NP_001271299.1  cyclic AMP-dependent transcription factor ATF-2 isoform 4

    See identical proteins and their annotated locations for NP_001271299.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) lacks an exon and its 3' terminal exon extends past a splice site that is used in variant 1. This results in a novel 3' coding region and 3' UTR, compared to variant 1. It encodes isoform 4 which is shorter and has a distinct C-terminus, compared to isoform 1. Variants 5 and 6 encode the same protein.
    Source sequence(s)
    AK035438, AK146839, AL844581, BY474294
    UniProtKB/TrEMBL
    G3UXC3, Q8CBR9
    Related
    ENSMUST00000143714.8
    Conserved Domains (3) summary
    cd12192
    Location:4784
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    cd14687
    Location:336377
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
    sd00019
    Location:931
    ZF_C2H2; C2H2 Zn finger [structural motif]
  4. NM_001284371.1NP_001271300.1  cyclic AMP-dependent transcription factor ATF-2 isoform 4

    See identical proteins and their annotated locations for NP_001271300.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR, lacks an exon, and its 3' terminal exon extends past a splice site that is used in variant 1. This results in a novel 3' coding region and 3' UTR, compared to variant 1. It encodes isoform 4 which is shorter and has a distinct C-terminus, compared to isoform 1. Variants 5 and 6 encode the same protein.
    Source sequence(s)
    AK035438, AK146839, AL844581, BY474294
    UniProtKB/TrEMBL
    G3UXC3, Q8CBR9
    Conserved Domains (3) summary
    cd12192
    Location:4784
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    cd14687
    Location:336377
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
    sd00019
    Location:931
    ZF_C2H2; C2H2 Zn finger [structural motif]
  5. NM_001284372.1NP_001271301.1  cyclic AMP-dependent transcription factor ATF-2 isoform 5

    See identical proteins and their annotated locations for NP_001271301.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) lacks two alternate in-frame exons compared to variant 1. The resulting protein (isoform 5) is shorter compared to isoform 1.
    Source sequence(s)
    AL844581, AL845523
    Consensus CDS
    CCDS71076.1
    UniProtKB/TrEMBL
    Q640L6
    Conserved Domains (3) summary
    cd12192
    Location:4784
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    cd14687
    Location:238298
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
    sd00019
    Location:931
    ZF_C2H2; C2H2 Zn finger [structural motif]
  6. NM_001284373.1NP_001271302.1  cyclic AMP-dependent transcription factor ATF-2 isoform 5

    See identical proteins and their annotated locations for NP_001271302.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR and lacks two alternate in-frame exons compared to variant 1. The resulting protein (isoform 5) is shorter compared to isoform 1.
    Source sequence(s)
    AL844581, BC079883, BC082596
    Consensus CDS
    CCDS71076.1
    UniProtKB/TrEMBL
    Q640L6
    Related
    ENSMUSP00000107647.3, ENSMUST00000112016.9
    Conserved Domains (3) summary
    cd12192
    Location:4784
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    cd14687
    Location:238298
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
    sd00019
    Location:931
    ZF_C2H2; C2H2 Zn finger [structural motif]
  7. NM_001284374.1NP_001271303.1  cyclic AMP-dependent transcription factor ATF-2 isoform 6

    Status: VALIDATED

    Description
    Transcript Variant: This variant (9) differs in the 5' UTR and lacks a 5' exon compared to variant 1. This variant represents translation initiation at a downstream AUG compared to variant 1; the 5'-most initiation codon, as used in variant 1, is associated with a truncated ORF that would render the transcript a candidate for nonsense-mediated decay (NMD). Leaky scanning may allow translation initiation at the downstream AUG. The resulting protein (isoform 6) has a shorter N-terminus compared to isoform 1.
    Source sequence(s)
    AL844581, AL845523, BC082596, BC085137
    UniProtKB/TrEMBL
    P70299
    Related
    ENSMUST00000156455.8
    Conserved Domains (1) summary
    cd14687
    Location:101161
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
  8. NM_001284376.1NP_001271305.1  cyclic AMP-dependent transcription factor ATF-2 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks an alternate in-frame exon, contains an alternate in-frame exon and uses a downstream start codon compared to variant 1. The resulting protein (isoform 3) is shorter compared to isoform 1.
    Source sequence(s)
    AL844581, AL845523, BC079883, BC082596
    UniProtKB/TrEMBL
    Q68FE3
    Conserved Domains (2) summary
    cd12192
    Location:944
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    cd14687
    Location:289349
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
  9. NM_009715.3NP_033845.1  cyclic AMP-dependent transcription factor ATF-2 isoform 2

    See identical proteins and their annotated locations for NP_033845.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region and uses a downstream start codon compared to variant 1. The resulting protein (isoform 2) is shorter compared to isoform 1.. Variants 2 and 3 encode the same protein.
    Source sequence(s)
    AK051591, AL844581, AL845523, BC079883
    Consensus CDS
    CCDS16135.1
    UniProtKB/TrEMBL
    Q543G2, Q68FE3
    Related
    ENSMUSP00000107638.2, ENSMUST00000112007.8
    Conserved Domains (3) summary
    cd12192
    Location:944
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    PRK14951
    Location:144272
    PRK14951; DNA polymerase III subunits gamma and tau; Provisional
    cd14687
    Location:296356
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    73646853..73723094 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030246850.2XP_030102710.1  cyclic AMP-dependent transcription factor ATF-2 isoform X3

    UniProtKB/TrEMBL
    G3UXC3
    Conserved Domains (4) summary
    cd12192
    Location:4784
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    cd14687
    Location:336382
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
    sd00019
    Location:931
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam05109
    Location:72331
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
  2. XM_030246847.2XP_030102707.1  cyclic AMP-dependent transcription factor ATF-2 isoform X3

    UniProtKB/TrEMBL
    G3UXC3
    Related
    ENSMUSP00000133632.2, ENSMUST00000173010.8
    Conserved Domains (4) summary
    cd12192
    Location:4784
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    cd14687
    Location:336382
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
    sd00019
    Location:931
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam05109
    Location:72331
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
  3. XM_030246840.2XP_030102700.1  cyclic AMP-dependent transcription factor ATF-2 isoform X1

    UniProtKB/Swiss-Prot
    P16951, Q64089, Q64090, Q64091
    UniProtKB/TrEMBL
    Q8CGB4
    Related
    ENSMUSP00000107648.2, ENSMUST00000112017.8
    Conserved Domains (4) summary
    cd12192
    Location:4784
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    PRK14951
    Location:184312
    PRK14951; DNA polymerase III subunits gamma and tau; Provisional
    cd14687
    Location:336396
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
    sd00019
    Location:931
    ZF_C2H2; C2H2 Zn finger [structural motif]
  4. XM_030246846.2XP_030102706.1  cyclic AMP-dependent transcription factor ATF-2 isoform X2

    UniProtKB/TrEMBL
    Q543G2, Q68FE3
    Related
    ENSMUSP00000088311.5, ENSMUST00000090802.11
    Conserved Domains (3) summary
    cd12192
    Location:944
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    PRK14951
    Location:144272
    PRK14951; DNA polymerase III subunits gamma and tau; Provisional
    cd14687
    Location:296356
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
  5. XM_036157694.1XP_036013587.1  cyclic AMP-dependent transcription factor ATF-2 isoform X1

    UniProtKB/Swiss-Prot
    P16951, Q64089, Q64090, Q64091
    UniProtKB/TrEMBL
    Q8CGB4
    Conserved Domains (4) summary
    cd12192
    Location:4784
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    PRK14951
    Location:184312
    PRK14951; DNA polymerase III subunits gamma and tau; Provisional
    cd14687
    Location:336396
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
    sd00019
    Location:931
    ZF_C2H2; C2H2 Zn finger [structural motif]
  6. XM_030246872.1XP_030102732.1  cyclic AMP-dependent transcription factor ATF-2 isoform X6

    Conserved Domains (2) summary
    cd12192
    Location:944
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    cd14687
    Location:198258
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
  7. XM_030246855.1XP_030102715.1  cyclic AMP-dependent transcription factor ATF-2 isoform X4

    UniProtKB/TrEMBL
    Q640L6
    Conserved Domains (3) summary
    cd12192
    Location:4784
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    cd14687
    Location:238298
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
    sd00019
    Location:931
    ZF_C2H2; C2H2 Zn finger [structural motif]
  8. XM_030246858.1XP_030102718.1  cyclic AMP-dependent transcription factor ATF-2 isoform X4

    UniProtKB/TrEMBL
    Q640L6
    Conserved Domains (3) summary
    cd12192
    Location:4784
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    cd14687
    Location:238298
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
    sd00019
    Location:931
    ZF_C2H2; C2H2 Zn finger [structural motif]
  9. XM_036157708.1XP_036013601.1  cyclic AMP-dependent transcription factor ATF-2 isoform X2

    UniProtKB/TrEMBL
    Q543G2, Q68FE3
    Conserved Domains (3) summary
    cd12192
    Location:944
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    PRK14951
    Location:144272
    PRK14951; DNA polymerase III subunits gamma and tau; Provisional
    cd14687
    Location:296356
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
  10. XM_030246843.2XP_030102703.1  cyclic AMP-dependent transcription factor ATF-2 isoform X1

    UniProtKB/Swiss-Prot
    P16951, Q64089, Q64090, Q64091
    UniProtKB/TrEMBL
    Q8CGB4
    Conserved Domains (4) summary
    cd12192
    Location:4784
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    PRK14951
    Location:184312
    PRK14951; DNA polymerase III subunits gamma and tau; Provisional
    cd14687
    Location:336396
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
    sd00019
    Location:931
    ZF_C2H2; C2H2 Zn finger [structural motif]
  11. XM_030246873.1XP_030102733.1  cyclic AMP-dependent transcription factor ATF-2 isoform X7

    Conserved Domains (2) summary
    cd12192
    Location:4784
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    cd14687
    Location:238284
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
  12. XM_036157711.1XP_036013604.1  cyclic AMP-dependent transcription factor ATF-2 isoform X5

    Conserved Domains (2) summary
    cd12192
    Location:1552
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    cd14687
    Location:206266
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
  13. XM_036157707.1XP_036013600.1  cyclic AMP-dependent transcription factor ATF-2 isoform X2

    UniProtKB/TrEMBL
    Q543G2, Q68FE3
    Conserved Domains (3) summary
    cd12192
    Location:944
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    PRK14951
    Location:144272
    PRK14951; DNA polymerase III subunits gamma and tau; Provisional
    cd14687
    Location:296356
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
  14. XM_036157712.1XP_036013605.1  cyclic AMP-dependent transcription factor ATF-2 isoform X6

    Conserved Domains (2) summary
    cd12192
    Location:944
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    cd14687
    Location:198258
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
  15. XM_036157709.1XP_036013602.1  cyclic AMP-dependent transcription factor ATF-2 isoform X4

    UniProtKB/TrEMBL
    Q640L6
    Conserved Domains (3) summary
    cd12192
    Location:4784
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    cd14687
    Location:238298
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
    sd00019
    Location:931
    ZF_C2H2; C2H2 Zn finger [structural motif]
  16. XM_036157691.1XP_036013584.1  cyclic AMP-dependent transcription factor ATF-2 isoform X1

    UniProtKB/Swiss-Prot
    P16951, Q64089, Q64090, Q64091
    UniProtKB/TrEMBL
    Q8CGB4
    Related
    ENSMUSP00000097588.5, ENSMUST00000100009.11
    Conserved Domains (4) summary
    cd12192
    Location:4784
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    PRK14951
    Location:184312
    PRK14951; DNA polymerase III subunits gamma and tau; Provisional
    cd14687
    Location:336396
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
    sd00019
    Location:931
    ZF_C2H2; C2H2 Zn finger [structural motif]
  17. XM_030246844.2XP_030102704.1  cyclic AMP-dependent transcription factor ATF-2 isoform X1

    UniProtKB/Swiss-Prot
    P16951, Q64089, Q64090, Q64091
    UniProtKB/TrEMBL
    Q8CGB4
    Conserved Domains (4) summary
    cd12192
    Location:4784
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    PRK14951
    Location:184312
    PRK14951; DNA polymerase III subunits gamma and tau; Provisional
    cd14687
    Location:336396
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
    sd00019
    Location:931
    ZF_C2H2; C2H2 Zn finger [structural motif]
  18. XM_030246853.2XP_030102713.1  cyclic AMP-dependent transcription factor ATF-2 isoform X4

    UniProtKB/TrEMBL
    Q640L6
    Conserved Domains (3) summary
    cd12192
    Location:4784
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    cd14687
    Location:238298
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
    sd00019
    Location:931
    ZF_C2H2; C2H2 Zn finger [structural motif]
  19. XM_030246841.2XP_030102701.1  cyclic AMP-dependent transcription factor ATF-2 isoform X1

    UniProtKB/Swiss-Prot
    P16951, Q64089, Q64090, Q64091
    UniProtKB/TrEMBL
    Q8CGB4
    Conserved Domains (4) summary
    cd12192
    Location:4784
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    PRK14951
    Location:184312
    PRK14951; DNA polymerase III subunits gamma and tau; Provisional
    cd14687
    Location:336396
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
    sd00019
    Location:931
    ZF_C2H2; C2H2 Zn finger [structural motif]
  20. XM_030246867.1XP_030102727.1  cyclic AMP-dependent transcription factor ATF-2 isoform X4

    UniProtKB/TrEMBL
    Q640L6
    Conserved Domains (3) summary
    cd12192
    Location:4784
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    cd14687
    Location:238298
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
    sd00019
    Location:931
    ZF_C2H2; C2H2 Zn finger [structural motif]
  21. XM_036157700.1XP_036013593.1  cyclic AMP-dependent transcription factor ATF-2 isoform X1

    UniProtKB/Swiss-Prot
    P16951, Q64089, Q64090, Q64091
    UniProtKB/TrEMBL
    Q8CGB4
    Conserved Domains (4) summary
    cd12192
    Location:4784
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    PRK14951
    Location:184312
    PRK14951; DNA polymerase III subunits gamma and tau; Provisional
    cd14687
    Location:336396
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
    sd00019
    Location:931
    ZF_C2H2; C2H2 Zn finger [structural motif]
  22. XM_036157713.1XP_036013606.1  cyclic AMP-dependent transcription factor ATF-2 isoform X8

    UniProtKB/TrEMBL
    A2AQF0
    Related
    ENSMUSP00000118560.2, ENSMUST00000128531.8
    Conserved Domains (2) summary
    cd12192
    Location:4784
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    sd00019
    Location:931
    ZF_C2H2; C2H2 Zn finger [structural motif]

RNA

  1. XR_004937562.1 RNA Sequence

External link. Please review our privacy policy.