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    sucB dihydrolipoyltranssuccinylase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945307, updated on 3-Dec-2024

    Summary

    Official Symbol
    sucB
    Official Full Name
    dihydrolipoyltranssuccinylase
    Primary source
    ECOCYC:EG10980
    Locus tag
    b0727
    See related
    ASAP:ABE-0002480
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0715
    Summary
    sucAB is a synthetic lethal with sucCD. [More information is available at EcoGene: EG10980]. The SucB subunit (E2o) of the 2-oxoglutarate dehydrogenase complex is responsible for the dihydrolipoamide succinyltransferase activity . [More information is available at EcoCyc: EG10980].
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    Genomic context

    Sequence:
    NC_000913.3 (761522..762739)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene succinate:quinone oxidoreductase, iron-sulfur cluster binding protein Neighboring gene subunit of E1(0) component of 2-oxoglutarate dehydrogenase Neighboring gene succinyl-CoA synthetase subunit beta Neighboring gene succinyl-CoA synthetase subunit alpha

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    General gene information

    Gene Ontology Provided by EcoCyc

    Component Evidence Code Pubs
    located_in cytoplasm PubMed 
    is_active_in cytosol  
    located_in cytosol PubMed 
    part_of oxoglutarate dehydrogenase complex PubMed 
    part_of oxoglutarate dehydrogenase complex  
    part_of oxoglutarate dehydrogenase complex PubMed 

    General protein information

    Preferred Names
    dihydrolipoyltranssuccinylase
    NP_415255.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      761522..762739
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      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415255.1 dihydrolipoyltranssuccinylase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415255.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A6C9QAQ1, A0A8S7ENK5
      Conserved Domains (1) summary
      PRK05704
      Location:2405
      PRK05704; 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase
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