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Sstr4 somatostatin receptor 4 [ Mus musculus (house mouse) ]

Gene ID: 20608, updated on 13-Jan-2025

Summary

Official Symbol
Sstr4provided by MGI
Official Full Name
somatostatin receptor 4provided by MGI
Primary source
MGI:MGI:105372
See related
Ensembl:ENSMUSG00000037014 AllianceGenome:MGI:105372
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
sst4; Smstr4
Summary
Predicted to enable neuropeptide binding activity and somatostatin receptor activity. Predicted to be involved in several processes, including neuropeptide signaling pathway; positive regulation of arachidonate secretion; and regulation of signal transduction. Predicted to be active in neuron projection and plasma membrane. Is expressed in several structures, including genitourinary system; gut; nervous system; respiratory system; and sensory organ. Orthologous to human SSTR4 (somatostatin receptor 4). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See Sstr4 in Genome Data Viewer
Location:
2 G3; 2 73.44 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (148237297..148238684)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (148395377..148396764)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 36597 Neighboring gene predicted gene, 39957 Neighboring gene STARR-seq mESC enhancer starr_05968 Neighboring gene STARR-positive B cell enhancer ABC_E9205 Neighboring gene STARR-seq mESC enhancer starr_05969 Neighboring gene STARR-seq mESC enhancer starr_05970 Neighboring gene STARR-positive B cell enhancer ABC_E5997 Neighboring gene thrombomodulin Neighboring gene STARR-positive B cell enhancer ABC_E2051 Neighboring gene CD93 antigen

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 
  • Targeted (5)  1 citation

Pathways from PubChem

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables neuropeptide binding  
enables protein binding PubMed 
enables somatostatin receptor activity  
enables somatostatin receptor activity  
enables somatostatin receptor activity  
Component Evidence Code Pubs
is_active_in neuron projection  
is_active_in plasma membrane  
located_in plasma membrane  

General protein information

Preferred Names
somatostatin receptor type 4
Names
SS-4-R
SS4-R
SS4R

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009219.3NP_033245.2  somatostatin receptor type 4

    See identical proteins and their annotated locations for NP_033245.2

    Status: PROVISIONAL

    Source sequence(s)
    AK051189, CB522494
    Consensus CDS
    CCDS38260.1
    UniProtKB/Swiss-Prot
    P49660, Q8BQ97
    UniProtKB/TrEMBL
    A0A0R4J1D6
    Related
    ENSMUSP00000105588.3, ENSMUST00000109962.4
    Conserved Domains (1) summary
    cd15973
    Location:45319
    7tmA_SSTR4; somatostatin receptor type 4, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    148237297..148238684
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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