Replication interactions
Interaction |
Pubs |
Knockdown of nucleoporin 62kDa (NUP62) by shRNA inhibits HIV-1 infection by reducing viral DNA integration in CD4+ C8166 T cells and macrophages |
PubMed
|
Knockdown of nucleoporin 62kDa (NUP62) by siRNA inhibits the early stages of HIV-1 replication in 293T cells infected with VSV-G pseudotyped HIV-1 |
PubMed
|
Protein interactions
Protein |
Gene |
Interaction |
Pubs |
Rev
|
rev
|
nup62 is involved in Rev-mediated nuclear export of HIV-1 mRNA through an interaction with eukaryotic initiation factor 5A (eIF-5A) which binds to Rev |
PubMed
|
integrase
|
gag-pol
|
HIV-1 IN specifically binds NUP62 through the IN binding domain (residues 328-522) of NUP62 |
PubMed
|
Go to the HIV-1, Human Interaction Database