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Kcnq2 potassium voltage-gated channel, subfamily Q, member 2 [ Mus musculus (house mouse) ]

Gene ID: 16536, updated on 4-Jan-2025

Summary

Official Symbol
Kcnq2provided by MGI
Official Full Name
potassium voltage-gated channel, subfamily Q, member 2provided by MGI
Primary source
MGI:MGI:1309503
See related
Ensembl:ENSMUSG00000016346 AllianceGenome:MGI:1309503
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
KQT2; HNSPC; Nmf134
Summary
Enables calmodulin binding activity; potassium channel activity; and voltage-gated monoatomic ion channel activity. Acts upstream of or within several processes, including chemical synaptic transmission; learning or memory; and nervous system development. Located in cell surface; main axon; and plasma membrane. Part of voltage-gated potassium channel complex. Is expressed in several structures, including brain; gut; immune system; reproductive system; and white fat. Used to study benign neonatal seizures and developmental and epileptic encephalopathy 7. Human ortholog(s) of this gene implicated in benign neonatal seizures and developmental and epileptic encephalopathy 7. Orthologous to human KCNQ2 (potassium voltage-gated channel subfamily Q member 2). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in cortex adult (RPKM 26.0), frontal lobe adult (RPKM 26.0) and 5 other tissues See more
Orthologs
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Genomic context

See Kcnq2 in Genome Data Viewer
Location:
2 H4; 2 103.57 cM
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (180717372..180777368, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (181075579..181135580, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene collagen, type XX, alpha 1 Neighboring gene cholinergic receptor, nicotinic, alpha polypeptide 4 Neighboring gene eukaryotic translation elongation factor 1 alpha 2 Neighboring gene predicted gene, 24892

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ankyrin binding  
enables calmodulin binding PubMed 
enables calmodulin binding PubMed 
enables calmodulin binding  
enables potassium channel activity PubMed 
enables potassium channel activity PubMed 
enables protein binding PubMed 
enables voltage-gated monoatomic cation channel activity  
enables voltage-gated monoatomic ion channel activity PubMed 
enables voltage-gated potassium channel activity  
enables voltage-gated potassium channel activity  
enables voltage-gated potassium channel activity  
Items 1 - 25 of 59
Process Evidence Code Pubs
acts_upstream_of_or_within action potential PubMed 
acts_upstream_of_or_within action potential PubMed 
acts_upstream_of_or_within action potential initiation PubMed 
acts_upstream_of_or_within action potential initiation PubMed 
acts_upstream_of_or_within action potential initiation PubMed 
acts_upstream_of_or_within apoptosome assembly PubMed 
acts_upstream_of_or_within behavior PubMed 
acts_upstream_of_or_within brain development PubMed 
acts_upstream_of_or_within cellular response to calcium ion PubMed 
acts_upstream_of_or_within cellular response to xenobiotic stimulus PubMed 
acts_upstream_of_or_within cognition PubMed 
acts_upstream_of_or_within dentate gyrus development PubMed 
acts_upstream_of_or_within determination of adult lifespan PubMed 
acts_upstream_of_or_within determination of adult lifespan PubMed 
acts_upstream_of_or_within endocytosis PubMed 
acts_upstream_of_or_within establishment of cell polarity PubMed 
acts_upstream_of_or_within excitatory chemical synaptic transmission PubMed 
acts_upstream_of_or_within excitatory chemical synaptic transmission PubMed 
acts_upstream_of_or_within exocytosis PubMed 
acts_upstream_of_or_within exploration behavior PubMed 
acts_upstream_of_or_within gene expression PubMed 
acts_upstream_of_or_within gene expression PubMed 
acts_upstream_of_or_within grooming behavior PubMed 
acts_upstream_of_or_within hippocampal pyramidal neuron differentiation PubMed 
acts_upstream_of_or_within hippocampus development PubMed 
acts_upstream_of_or_within inhibitory chemical synaptic transmission PubMed 
acts_upstream_of_or_within learning PubMed 
acts_upstream_of_or_within membrane hyperpolarization  
acts_upstream_of_or_within memory PubMed 
acts_upstream_of_or_within mitochondrial depolarization PubMed 
acts_upstream_of_or_within monoatomic ion transmembrane transport PubMed 
acts_upstream_of_or_within motor behavior PubMed 
acts_upstream_of_or_within nerve development PubMed 
acts_upstream_of_or_within nerve development PubMed 
acts_upstream_of_or_within neuron apoptotic process PubMed 
acts_upstream_of_or_within neuron differentiation PubMed 
acts_upstream_of_or_within neuron remodeling PubMed 
acts_upstream_of_or_within neuronal action potential PubMed 
involved_in potassium ion transmembrane transport  
involved_in potassium ion transmembrane transport  
involved_in potassium ion transmembrane transport  
acts_upstream_of_or_within protein import into nucleus PubMed 
acts_upstream_of_or_within protein phosphorylation PubMed 
acts_upstream_of_or_within protein transport PubMed 
acts_upstream_of_or_within psychomotor behavior PubMed 
acts_upstream_of_or_within regulation of action potential firing threshold PubMed 
acts_upstream_of_or_within regulation of membrane potential PubMed 
acts_upstream_of_or_within regulation of synaptic plasticity PubMed 
acts_upstream_of_or_within response to auditory stimulus PubMed 
acts_upstream_of_or_within response to auditory stimulus PubMed 
acts_upstream_of_or_within response to mechanical stimulus PubMed 
acts_upstream_of_or_within response to organic cyclic compound PubMed 
acts_upstream_of_or_within response to temperature stimulus PubMed 
acts_upstream_of_or_within response to xenobiotic stimulus PubMed 
acts_upstream_of_or_within sensory perception of sound PubMed 
acts_upstream_of_or_within social behavior PubMed 
acts_upstream_of_or_within sodium ion transmembrane transport PubMed 
acts_upstream_of_or_within substantia propria of cornea development PubMed 
acts_upstream_of_or_within transmission of nerve impulse PubMed 
Items 1 - 25 of 59
Component Evidence Code Pubs
is_active_in axon initial segment PubMed 
located_in axon initial segment PubMed 
located_in axon initial segment  
located_in cell surface PubMed 
located_in mitochondrion  
is_active_in node of Ranvier PubMed 
located_in node of Ranvier PubMed 
located_in plasma membrane PubMed 
located_in plasma membrane  
located_in synapse  
part_of voltage-gated potassium channel complex  
part_of voltage-gated potassium channel complex PubMed 
part_of voltage-gated potassium channel complex  
part_of voltage-gated potassium channel complex  

General protein information

Preferred Names
potassium voltage-gated channel subfamily KQT member 2
Names
KQT-like 2
potassium channel subunit alpha KvLQT2
voltage-gated potassium channel subunit Kv7.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003824.2NP_001003824.1  potassium voltage-gated channel subfamily KQT member 2 isoform 2

    See identical proteins and their annotated locations for NP_001003824.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks two alternate in-frame exons but includes an additional in-frame exon, and it also contains alternate 3' exon structure resulting in an alternate 3' coding region, compared to variant 1. The encoded isoform (2) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AL450341, BC145453, CJ121810, CJ263767
    Consensus CDS
    CCDS17193.1
    UniProtKB/Swiss-Prot
    Q3UTI0, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350, Q9Z351
    UniProtKB/TrEMBL
    B7ZBV4
    Related
    ENSMUSP00000016491.8, ENSMUST00000016491.14
    Conserved Domains (4) summary
    pfam00520
    Location:119324
    Ion_trans; Ion transport protein
    pfam03520
    Location:444666
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam07885
    Location:240314
    Ion_trans_2; Ion channel
    pfam16642
    Location:675754
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  2. NM_001003825.3NP_001003825.1  potassium voltage-gated channel subfamily KQT member 2 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks two alternate in-frame exons and uses an alternate in-frame splice site, and it also contains alternate 3' exon structure resulting in an alternate 3' coding region, compared to variant 1. The encoded isoform (3) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AL450341, CJ119072, CJ121810, CJ263767
    Consensus CDS
    CCDS17194.1
    UniProtKB/Swiss-Prot
    Q3UTI0, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350, Q9Z351
    UniProtKB/TrEMBL
    B7ZBV6
    Related
    ENSMUSP00000052453.9, ENSMUST00000049792.15
    Conserved Domains (4) summary
    pfam00520
    Location:119324
    Ion_trans; Ion transport protein
    pfam03520
    Location:444661
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam07885
    Location:240314
    Ion_trans_2; Ion channel
    pfam16642
    Location:670749
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  3. NM_001006668.2NP_001006669.1  potassium voltage-gated channel subfamily KQT member 2 isoform 4

    See identical proteins and their annotated locations for NP_001006669.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks two alternate in-frame exons but includes an additional in-frame exon, it uses an alternate in-frame splice site, and it also contains alternate 3' exon structure resulting in an alternate 3' coding region, compared to variant 1. The encoded isoform (4) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AL450341, CJ119072, CJ121810, CJ263767
    Consensus CDS
    CCDS17195.1
    UniProtKB/Swiss-Prot
    Q3UTI0, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350, Q9Z351
    UniProtKB/TrEMBL
    B7ZBV8
    Related
    ENSMUSP00000099336.4, ENSMUST00000103047.10
    Conserved Domains (4) summary
    pfam00520
    Location:119324
    Ion_trans; Ion transport protein
    pfam03520
    Location:432654
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam07885
    Location:240314
    Ion_trans_2; Ion channel
    pfam16642
    Location:663742
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  4. NM_001006669.2NP_001006670.1  potassium voltage-gated channel subfamily KQT member 2 isoform 5

    See identical proteins and their annotated locations for NP_001006670.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) lacks two alternate in-frame exons, and it also contains alternate 3' exon structure resulting in an alternate 3' coding region, compared to variant 1. The encoded isoform (5) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AL450341, CJ119072, CJ121810, CJ263767
    Consensus CDS
    CCDS17196.1
    UniProtKB/Swiss-Prot
    Q3UTI0, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350, Q9Z351
    UniProtKB/TrEMBL
    B7ZBV7
    Related
    ENSMUSP00000099337.4, ENSMUST00000103048.10
    Conserved Domains (4) summary
    pfam00520
    Location:119324
    Ion_trans; Ion transport protein
    pfam03520
    Location:444630
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam07885
    Location:240314
    Ion_trans_2; Ion channel
    pfam16642
    Location:639718
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  5. NM_001006674.2NP_001006675.1  potassium voltage-gated channel subfamily KQT member 2 isoform 6

    See identical proteins and their annotated locations for NP_001006675.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) lacks two alternate in-frame exons, and it also contains alternate 3' exon structure resulting in an alternate 3' coding region, compared to variant 1. The encoded isoform (6) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AL450341, CJ119072, CJ121810, CJ263767
    Consensus CDS
    CCDS17197.1
    UniProtKB/TrEMBL
    B7ZBV5
    Related
    ENSMUSP00000080243.7, ENSMUST00000081528.13
    Conserved Domains (3) summary
    pfam00520
    Location:119324
    Ion_trans; Ion transport protein
    pfam03520
    Location:444561
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam07885
    Location:240314
    Ion_trans_2; Ion channel
  6. NM_001302888.1NP_001289817.1  potassium voltage-gated channel subfamily KQT member 2 isoform 13

    Status: VALIDATED

    Description
    Transcript Variant: This variant (13) lacks an alternate in-frame exon and uses an alternate in-frame splice site, resulting in an isoform (13) that is shorter than isoform 1.
    Source sequence(s)
    AK139411, AL450341, CJ119072, CJ121810, CJ263767
    UniProtKB/TrEMBL
    F6UC55
    Related
    ENSMUSP00000099338.4, ENSMUST00000103049.10
    Conserved Domains (5) summary
    pfam00520
    Location:119324
    Ion_trans; Ion transport protein
    pfam03520
    Location:454639
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam07885
    Location:240314
    Ion_trans_2; Ion channel
    pfam11956
    Location:757847
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:648735
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  7. NM_001420340.1NP_001407269.1  potassium voltage-gated channel subfamily KQT member 2 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AL450341
  8. NM_001420341.1NP_001407270.1  potassium voltage-gated channel subfamily KQT member 2 isoform 14

    Status: VALIDATED

    Source sequence(s)
    AL450341
  9. NM_001420342.1NP_001407271.1  potassium voltage-gated channel subfamily KQT member 2 isoform 15

    Status: VALIDATED

    Source sequence(s)
    AL450341
  10. NM_010611.3NP_034741.2  potassium voltage-gated channel subfamily KQT member 2 isoform 1

    See identical proteins and their annotated locations for NP_034741.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AK135059, AK139411, AL450341, CJ119072, CJ121810, CJ125938, CJ263767
    Consensus CDS
    CCDS17198.1
    UniProtKB/TrEMBL
    B7ZBV9, F6UC55
    Related
    ENSMUSP00000122915.3, ENSMUST00000149964.9
    Conserved Domains (5) summary
    pfam00520
    Location:119324
    Ion_trans; Ion transport protein
    pfam03520
    Location:472658
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam07885
    Location:240314
    Ion_trans_2; Ion channel
    pfam11956
    Location:776866
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:667754
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    180717372..180777368 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017315767.3XP_017171256.1  potassium voltage-gated channel subfamily KQT member 2 isoform X24

    UniProtKB/TrEMBL
    F6UC55
    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:426612
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:733826
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:627714
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  2. XM_017315754.3XP_017171243.1  potassium voltage-gated channel subfamily KQT member 2 isoform X17

    UniProtKB/TrEMBL
    F6UC55
    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:426648
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:769862
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:663750
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  3. XM_030247788.2XP_030103648.1  potassium voltage-gated channel subfamily KQT member 2 isoform X21

    UniProtKB/TrEMBL
    F6UC55
    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:438623
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:744837
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:638725
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  4. XM_030247775.2XP_030103635.1  potassium voltage-gated channel subfamily KQT member 2 isoform X9

    UniProtKB/TrEMBL
    F6UC55
    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:438690
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:811904
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:705792
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  5. XM_006500567.3XP_006500630.1  potassium voltage-gated channel subfamily KQT member 2 isoform X20

    UniProtKB/TrEMBL
    A0A0G2JFQ2, F6UC55
    Related
    ENSMUSP00000143263.2, ENSMUST00000197015.5
    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:438624
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:745838
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:639726
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  6. XM_017315747.3XP_017171236.1  potassium voltage-gated channel subfamily KQT member 2 isoform X14

    UniProtKB/TrEMBL
    F6UC55
    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:438660
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:781874
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:675762
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  7. XM_017315751.3XP_017171240.1  potassium voltage-gated channel subfamily KQT member 2 isoform X15

    UniProtKB/TrEMBL
    F6UC55
    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:438655
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:776869
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:670757
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  8. XM_017315743.3XP_017171232.1  potassium voltage-gated channel subfamily KQT member 2 isoform X8

    UniProtKB/TrEMBL
    F6UC55
    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:438691
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:812905
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:706793
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  9. XM_036158776.1XP_036014669.1  potassium voltage-gated channel subfamily KQT member 2 isoform X18

    UniProtKB/TrEMBL
    F6UC55
    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:456641
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:755855
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:656743
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  10. XM_030247769.2XP_030103629.1  potassium voltage-gated channel subfamily KQT member 2 isoform X4

    UniProtKB/TrEMBL
    F6UC55
    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:456708
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:829922
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:723810
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  11. XM_017315740.3XP_017171229.1  potassium voltage-gated channel subfamily KQT member 2 isoform X3

    UniProtKB/TrEMBL
    F6UC55
    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:456709
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:830923
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:724811
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  12. XM_006500568.3XP_006500631.1  potassium voltage-gated channel subfamily KQT member 2 isoform X23

    UniProtKB/TrEMBL
    B7ZBW2, F6UC55
    Related
    ENSMUSP00000099339.5, ENSMUST00000103050.10
    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:436621
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:742835
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:636723
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  13. XM_017315763.3XP_017171252.1  potassium voltage-gated channel subfamily KQT member 2 isoform X22

    UniProtKB/TrEMBL
    F6UC55
    Related
    ENSMUSP00000123488.2, ENSMUST00000129695.8
    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:436622
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:743836
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:637724
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  14. XM_017315744.3XP_017171233.1  potassium voltage-gated channel subfamily KQT member 2 isoform X10

    UniProtKB/TrEMBL
    F6UC55
    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:436689
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:810903
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:704791
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  15. XM_030247772.2XP_030103632.1  potassium voltage-gated channel subfamily KQT member 2 isoform X7

    UniProtKB/TrEMBL
    F6UC55
    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:448700
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:821914
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:715802
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  16. XM_006500565.3XP_006500628.1  potassium voltage-gated channel subfamily KQT member 2 isoform X19

    UniProtKB/TrEMBL
    B7ZBW1, F6UC55
    Related
    ENSMUSP00000099340.3, ENSMUST00000103051.9
    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:448634
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:755848
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:649736
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  17. XM_036158772.1XP_036014665.1  potassium voltage-gated channel subfamily KQT member 2 isoform X13

    UniProtKB/TrEMBL
    F6UC55
    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:448670
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:784884
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:685772
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  18. XM_017315742.3XP_017171231.1  potassium voltage-gated channel subfamily KQT member 2 isoform X6

    UniProtKB/TrEMBL
    F6UC55
    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:448701
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:822915
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:716803
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  19. XM_017315741.3XP_017171230.1  potassium voltage-gated channel subfamily KQT member 2 isoform X5

    UniProtKB/TrEMBL
    F6UC55
    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:454707
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:828921
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:722809
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  20. XM_017315753.3XP_017171242.1  potassium voltage-gated channel subfamily KQT member 2 isoform X16

    UniProtKB/TrEMBL
    F6UC55
    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:466651
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:772865
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:666753
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  21. XM_017315738.3XP_017171227.1  potassium voltage-gated channel subfamily KQT member 2 isoform X2

    UniProtKB/TrEMBL
    F6UC55
    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:466718
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:839932
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:733820
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  22. XM_011239925.3XP_011238227.1  potassium voltage-gated channel subfamily KQT member 2 isoform X11

    UniProtKB/TrEMBL
    F6UC55
    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:466688
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:809902
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:703790
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  23. XM_017315746.3XP_017171235.1  potassium voltage-gated channel subfamily KQT member 2 isoform X12

    UniProtKB/TrEMBL
    F6UC55
    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:466683
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:804897
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:698785
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  24. XM_017315735.3XP_017171224.1  potassium voltage-gated channel subfamily KQT member 2 isoform X1

    UniProtKB/TrEMBL
    F6UC55
    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:466719
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:840933
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:734821
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  25. XM_030247798.2XP_030103658.1  potassium voltage-gated channel subfamily KQT member 2 isoform X26

    UniProtKB/TrEMBL
    B7ZBV3
    Conserved Domains (4) summary
    pfam00520
    Location:1151
    Ion_trans; Ion transport protein
    pfam03520
    Location:265518
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:639732
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:533620
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  26. XM_036158780.1XP_036014673.1  potassium voltage-gated channel subfamily KQT member 2 isoform X27

    Conserved Domains (3) summary
    pfam03520
    Location:17270
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:384484
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:285372
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  27. XM_030247797.1XP_030103657.1  potassium voltage-gated channel subfamily KQT member 2 isoform X25

    UniProtKB/TrEMBL
    B7ZBV3
    Conserved Domains (4) summary
    pfam00520
    Location:1151
    Ion_trans; Ion transport protein
    pfam03520
    Location:293546
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:667760
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:561648
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  28. XM_017315771.3XP_017171260.1  potassium voltage-gated channel subfamily KQT member 2 isoform X27

    Conserved Domains (3) summary
    pfam03520
    Location:17270
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:384484
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:285372
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  29. XM_017315781.3XP_017171270.1  potassium voltage-gated channel subfamily KQT member 2 isoform X28

    Conserved Domains (3) summary
    pfam03520
    Location:17269
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:390483
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:284371
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  30. XM_017315772.3XP_017171261.1  potassium voltage-gated channel subfamily KQT member 2 isoform X27

    Conserved Domains (3) summary
    pfam03520
    Location:17270
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:384484
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:285372
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  31. XM_017315776.3XP_017171265.1  potassium voltage-gated channel subfamily KQT member 2 isoform X27

    Conserved Domains (3) summary
    pfam03520
    Location:17270
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:384484
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:285372
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  32. XM_017315773.3XP_017171262.1  potassium voltage-gated channel subfamily KQT member 2 isoform X27

    Conserved Domains (3) summary
    pfam03520
    Location:17270
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:384484
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:285372
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2

RNA

  1. XR_003950848.2 RNA Sequence

  2. XR_004938437.1 RNA Sequence

  3. XR_004938426.1 RNA Sequence

  4. XR_004938432.1 RNA Sequence

  5. XR_001781086.3 RNA Sequence

  6. XR_001781085.3 RNA Sequence

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