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Srek1ip1 SREK1-interacting protein 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 361888, updated on 4-Jan-2025

Summary

Official Symbol
Srek1ip1provided by RGD
Official Full Name
SREK1-interacting protein 1provided by RGD
Primary source
RGD:1305356
See related
EnsemblRapid:ENSRNOG00000047506 AllianceGenome:RGD:1305356
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
P18srp; Sfrs12ip1; RGD1305356
Summary
Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to be involved in RNA splicing and mRNA processing. Orthologous to human SREK1IP1 (SREK1 interacting protein 1). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Thymus (RPKM 135.9), Spleen (RPKM 134.1) and 9 other tissues See more
Orthologs
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Genomic context

See Srek1ip1 in Genome Data Viewer
Location:
2q13
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (37709712..37733391)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (35975978..35999636)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (34923187..34940410)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein S29, pseudogene 14 Neighboring gene CWC27 spliceosome associated cyclophilin Neighboring gene shisa like 2B Neighboring gene regulator of G-protein signaling 7 binding protein

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Clone Names

  • MGC105985

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables nucleic acid binding  
enables zinc ion binding  
Process Evidence Code Pubs
involved_in RNA splicing  
involved_in mRNA processing  

General protein information

Preferred Names
protein SREK1IP1
Names
SFRS12-interacting protein 1
protein SFRS12IP1
splicing regulatory glutamine/lysine-rich protein 1 interacting protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008373.2NP_001008374.1  protein SREK1IP1

    See identical proteins and their annotated locations for NP_001008374.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/Swiss-Prot
    Q5RJP9
    UniProtKB/TrEMBL
    A0A8I6AEB3, A6I5G3
    Related
    ENSRNOP00000064069.3, ENSRNOT00000074499.4
    Conserved Domains (1) summary
    pfam13917
    Location:930
    zf-CCHC_3; Zinc knuckle

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    37709712..37733391
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063282031.1XP_063138101.1  protein SREK1IP1 isoform X1

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