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Steep1 STING1 ER exit protein 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 313433, updated on 4-Jan-2025

Summary

Official Symbol
Steep1provided by RGD
Official Full Name
STING1 ER exit protein 1provided by RGD
Primary source
RGD:1564541
See related
EnsemblRapid:ENSRNOG00000012564 AllianceGenome:RGD:1564541
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1564541
Summary
Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in endoplasmic reticulum membrane organization; endoplasmic reticulum to Golgi vesicle-mediated transport; and protein exit from endoplasmic reticulum. Predicted to be located in several cellular components, including cell body; centrosome; and nucleoplasm. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 107. Orthologous to human STEEP1 (STING1 ER exit protein 1). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Lung (RPKM 111.7), Kidney (RPKM 106.2) and 9 other tissues See more
Orthologs
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Genomic context

See Steep1 in Genome Data Viewer
Location:
Xq34
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (120953335..120979861, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (116087626..116114159, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (123460280..123486814, complement)

Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene transfer RNA proline (anticodon AGG) 76 Neighboring gene uncharacterized LOC134484096 Neighboring gene solute carrier family 25 member 5 Neighboring gene ubiquitin-conjugating enzyme E2A Neighboring gene NFKB repressing factor

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in cell body  
located_in centrosome  
located_in centrosome  
located_in cytoplasm  
is_active_in endoplasmic reticulum  
is_active_in endoplasmic reticulum membrane  
located_in nucleoplasm  
located_in nucleoplasm  
located_in nucleus  

General protein information

Preferred Names
STING ER exit protein
Names
UPF0428 protein CXorf56 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107950.1 → NP_001101420.1  STING ER exit protein

    See identical proteins and their annotated locations for NP_001101420.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473991
    UniProtKB/TrEMBL
    A0A0U1RS26, A6JMG2, A6JMG3, D4A067
    Related
    ENSRNOP00000016993.4, ENSRNOT00000016993.7

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086039.1 Reference GRCr8

    Range
    120953335..120979861 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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