U.S. flag

An official website of the United States government

Ndfip2 Nedd4 family interacting protein 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 361089, updated on 4-Jan-2025

Summary

Official Symbol
Ndfip2provided by RGD
Official Full Name
Nedd4 family interacting protein 2provided by RGD
Primary source
RGD:1309716
See related
EnsemblRapid:ENSRNOG00000024022 AllianceGenome:RGD:1309716
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable WW domain binding activity. Predicted to be involved in several processes, including negative regulation of transport; positive regulation of canonical NF-kappaB signal transduction; and regulation of macromolecule metabolic process. Predicted to be located in mitochondrion. Predicted to be active in Golgi apparatus; endoplasmic reticulum; and perinuclear region of cytoplasm. Orthologous to human NDFIP2 (Nedd4 family interacting protein 2). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Brain (RPKM 280.0), Kidney (RPKM 215.0) and 9 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Ndfip2 in Genome Data Viewer
Location:
15q22
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (88394548..88500881)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (82032366..82087043)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (89407426..89458983)

Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene ATP synthase subunit g, mitochondrial-like Neighboring gene ribosomal protein S11, pseudogene 8 Neighboring gene uncharacterized LOC134482160 Neighboring gene uncharacterized LOC120097070 Neighboring gene uncharacterized LOC134482161 Neighboring gene transfer RNA proline (anticodon AGG) 90 Neighboring gene ribosomal protein L9, pseudogene 14 Neighboring gene small ribosomal subunit protein uS15-like

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Component Evidence Code Pubs
is_active_in Golgi apparatus  
located_in Golgi apparatus  
located_in cytoplasm  
is_active_in endoplasmic reticulum  
located_in endoplasmic reticulum  
located_in intracellular membrane-bounded organelle  
located_in membrane  
located_in mitochondrion  
is_active_in perinuclear region of cytoplasm  
located_in perinuclear region of cytoplasm  

General protein information

Preferred Names
NEDD4 family-interacting protein 2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108390.2NP_001101860.2  NEDD4 family-interacting protein 2

    Status: VALIDATED

    Source sequence(s)
    BP495172, CB697675, CO398212, DV728397, DY565248, FM044778
    UniProtKB/TrEMBL
    F1M1W4
    Related
    ENSRNOP00000032094.6, ENSRNOT00000039423.7

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086033.1 Reference GRCr8

    Range
    88394548..88500881
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063274468.1XP_063130538.1  NEDD4 family-interacting protein 2 isoform X1

    Related
    ENSRNOP00000078524.2, ENSRNOT00000104952.2
  2. XM_063274469.1XP_063130539.1  NEDD4 family-interacting protein 2 isoform X1

External link. Please review our privacy policy.