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Aqp12a aquaporin 12A [ Rattus norvegicus (Norway rat) ]

Gene ID: 367316, updated on 4-Jan-2025

Summary

Official Symbol
Aqp12aprovided by RGD
Official Full Name
aquaporin 12Aprovided by RGD
Primary source
RGD:1562727
See related
EnsemblRapid:ENSRNOG00000004452 AllianceGenome:RGD:1562727
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Aqp12; Aqp12b; RGD1562727
Summary
Predicted to enable channel activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Predicted to be active in cytoplasm. Orthologous to several human genes including AQP12A (aquaporin 12A). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Spleen (RPKM 27.8), Liver (RPKM 9.6) and 1 other tissue See more
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Genomic context

See Aqp12a in Genome Data Viewer
Location:
9q36
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (101001939..101007425)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (93554527..93560011)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (100156154..100166218)

Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene G protein-coupled receptor 35 Neighboring gene kinesin family member 1A Neighboring gene alanine--glyoxylate aminotransferase

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Related articles in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables channel activity  
Component Evidence Code Pubs
is_active_in cytoplasm  
located_in cytoplasm  
located_in membrane  

General protein information

Preferred Names
aquaporin-12
Names
aquaporin 12B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109009.1NP_001102479.1  aquaporin-12

    See identical proteins and their annotated locations for NP_001102479.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473997
    UniProtKB/TrEMBL
    A6JQX3, D4A9T6
    Related
    ENSRNOP00000005935.3, ENSRNOT00000005935.5
    Conserved Domains (1) summary
    cl00200
    Location:116251
    MIP; Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086027.1 Reference GRCr8

    Range
    101001939..101007425
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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