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Zfp105 zinc finger protein 105 [ Rattus norvegicus (Norway rat) ]

Gene ID: 316096, updated on 4-Jan-2025

Summary

Official Symbol
Zfp105provided by RGD
Official Full Name
zinc finger protein 105provided by RGD
Primary source
RGD:1309905
See related
EnsemblRapid:ENSRNOG00000079667 AllianceGenome:RGD:1309905
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in cellular response to retinoic acid; regulation of transcription by RNA polymerase II; and spermatogenesis. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in nucleus. Orthologous to human ZNF35 (zinc finger protein 35). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Lung (RPKM 86.6), Kidney (RPKM 81.9) and 9 other tissues See more
Orthologs
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Genomic context

See Zfp105 in Genome Data Viewer
Location:
8q32
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (131444692..131456159)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (122567229..122578696)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (131998787..132009987)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene zinc finger with KRAB and SCAN domains 7 Neighboring gene zinc finger protein 660 Neighboring gene heterogeneous nuclear ribonucleoprotein A1, pseudogene 36 Neighboring gene ribosomal protein L7, pseudogene 3

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in biological_process  
involved_in cellular response to retinoic acid  
involved_in regulation of transcription by RNA polymerase II  
involved_in spermatogenesis  
Component Evidence Code Pubs
is_active_in nucleus  
located_in nucleus  
located_in nucleus  
located_in perinuclear region of cytoplasm  
located_in perinuclear region of cytoplasm  

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012128.2NP_001012128.1  zinc finger protein 35

    See identical proteins and their annotated locations for NP_001012128.1

    Status: VALIDATED

    Source sequence(s)
    BC088185, DY310202
    UniProtKB/TrEMBL
    F7FKJ4, Q5M881
    Related
    ENSRNOP00000109569.1, ENSRNOT00000168577.1
    Conserved Domains (4) summary
    COG5048
    Location:186366
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:333353
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:331353
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:373398
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    131444692..131456159
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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