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Hnrnpdl heterogeneous nuclear ribonucleoprotein D-like [ Rattus norvegicus (Norway rat) ]

Gene ID: 305178, updated on 4-Jan-2025

Summary

Official Symbol
Hnrnpdlprovided by RGD
Official Full Name
heterogeneous nuclear ribonucleoprotein D-likeprovided by RGD
Primary source
RGD:1309950
See related
EnsemblRapid:ENSRNOG00000002270 AllianceGenome:RGD:1309950
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Hnrpdl; hnRNP DL
Summary
Predicted to enable nucleic acid binding activity. Predicted to be involved in regulation of gene expression. Predicted to be located in chromatin and nucleus. Predicted to be active in nucleoplasm and synapse. Human ortholog(s) of this gene implicated in autosomal dominant limb-girdle muscular dystrophy type 3. Orthologous to human HNRNPDL (heterogeneous nuclear ribonucleoprotein D like). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Thymus (RPKM 364.6), Spleen (RPKM 248.0) and 9 other tissues See more
Orthologs
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Genomic context

See Hnrnpdl in Genome Data Viewer
Location:
14p22
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (9861716..9867945)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (9557430..9563659)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (11199114..11204670)

Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 150C Neighboring gene uncharacterized LOC134481706 Neighboring gene uncharacterized LOC134481708 Neighboring gene enolase-phosphatase 1 Neighboring gene heterogeneous nuclear ribonucleoprotein D Neighboring gene histone chaperone ASF1A-like Neighboring gene transcription factor BTF3-like Neighboring gene vesicle-associated membrane protein 9

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Interactions

General gene information

Clone Names

  • MGC125262

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA binding  
enables RNA binding  
enables RNA binding  
enables double-stranded DNA binding  
enables poly(A) binding  
enables poly(G) binding  
enables single-stranded DNA binding  
Process Evidence Code Pubs
involved_in regulation of gene expression  
involved_in regulation of gene expression  
Component Evidence Code Pubs
located_in chromatin  
located_in cytoplasm  
is_active_in nucleoplasm  
located_in nucleoplasm  
located_in nucleus  
located_in nucleus  
is_active_in synapse  

General protein information

Preferred Names
heterogeneous nuclear ribonucleoprotein D-like
Names
hnRNP D-like
hnRNP-DL
hnRPD-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033696.2NP_001028868.1  heterogeneous nuclear ribonucleoprotein D-like isoform 1

    See identical proteins and their annotated locations for NP_001028868.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000014
    UniProtKB/Swiss-Prot
    Q3SWU3
    UniProtKB/TrEMBL
    A6K617
    Related
    ENSRNOP00000003106.5, ENSRNOT00000003106.8
    Conserved Domains (2) summary
    cd12585
    Location:137211
    RRM2_hnRPDL; RNA recognition motif 2 (RRM2) found in heterogeneous nuclear ribonucleoprotein D-like (hnRNP DL) and similar proteins
    cd12758
    Location:52127
    RRM1_hnRPDL; RNA recognition motif 1 (RRM1) found in heterogeneous nuclear ribonucleoprotein D-like (hnRNP D-like or hnRNP DL) and similar proteins
  2. NM_001401448.1NP_001388377.1  heterogeneous nuclear ribonucleoprotein D-like isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000014
    UniProtKB/Swiss-Prot
    Q3SWU3
    UniProtKB/TrEMBL
    A6K617
  3. NM_001401449.1NP_001388378.1  heterogeneous nuclear ribonucleoprotein D-like isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000014
    UniProtKB/TrEMBL
    A0A0G2KAZ7, A0A8I6G5P1
  4. NM_001401450.1NP_001388379.1  heterogeneous nuclear ribonucleoprotein D-like isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000014
    UniProtKB/TrEMBL
    A0A0G2KAZ7, A0A8I6G5P1
    Related
    ENSRNOP00000075589.1, ENSRNOT00000079767.3
  5. NM_001401451.1NP_001388380.1  heterogeneous nuclear ribonucleoprotein D-like isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000014
    UniProtKB/TrEMBL
    A0A0G2KAZ7, A0A8I6G5P1

RNA

  1. NR_174877.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000014

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086032.1 Reference GRCr8

    Range
    9861716..9867945
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063273051.1XP_063129121.1  heterogeneous nuclear ribonucleoprotein D-like isoform X1

    UniProtKB/TrEMBL
    A0A8I6G5P1
  2. XM_063273052.1XP_063129122.1  heterogeneous nuclear ribonucleoprotein D-like isoform X2

RNA

  1. XR_005492930.2 RNA Sequence

  2. XR_359349.5 RNA Sequence

  3. XR_010057363.1 RNA Sequence

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