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Nudt14 nudix hydrolase 14 [ Rattus norvegicus (Norway rat) ]

Gene ID: 299346, updated on 4-Jan-2025

Summary

Official Symbol
Nudt14provided by RGD
Official Full Name
nudix hydrolase 14provided by RGD
Primary source
RGD:1310583
See related
EnsemblRapid:ENSRNOG00000014362 AllianceGenome:RGD:1310583
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable ADP-ribose diphosphatase activity; UDP-sugar diphosphatase activity; and identical protein binding activity. Predicted to be involved in nucleoside phosphate metabolic process and ribose phosphate metabolic process. Orthologous to human NUDT14 (nudix hydrolase 14). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Kidney (RPKM 163.5), Lung (RPKM 131.9) and 9 other tissues See more
Orthologs
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Genomic context

See Nudt14 in Genome Data Viewer
Location:
6q32
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (137831382..137838370, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (132010309..132017298, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (137738150..137745143, complement)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene keratin-associated protein 5-9-like Neighboring gene jagged canonical Notch ligand 2 Neighboring gene BRF1 general transcription factor IIIB subunit Neighboring gene BTB domain containing 6 Neighboring gene phosphofurin acidic cluster sorting protein 2 Neighboring gene uncharacterized LOC134479482

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ADP-ribose diphosphatase activity  
enables UDP-sugar diphosphatase activity  
enables UDP-sugar diphosphatase activity  
enables identical protein binding  
enables metal ion binding  
Process Evidence Code Pubs
involved_in nucleoside phosphate metabolic process  
involved_in ribose phosphate metabolic process  

General protein information

Preferred Names
uridine diphosphate glucose pyrophosphatase NUDT14
Names
nudix (nucleoside diphosphate linked moiety X)-type motif 14
nudix-type motif 14
uridine diphosphate glucose pyrophosphatase
NP_001100230.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106760.1NP_001100230.1  uridine diphosphate glucose pyrophosphatase NUDT14

    See identical proteins and their annotated locations for NP_001100230.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474034
    UniProtKB/TrEMBL
    A0A8I6G8A4, A6KBX1, D4A1D4
    Related
    ENSRNOP00000019550.5, ENSRNOT00000019550.8
    Conserved Domains (1) summary
    TIGR00052
    Location:23210
    TIGR00052; nudix-type nucleoside diphosphatase, YffH/AdpP family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    137831382..137838370 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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