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polq-1 DNA polymerase theta [ Caenorhabditis elegans ]

Gene ID: 175810, updated on 4-Jan-2025

Summary

Official Symbol
polq-1
Official Full Name
DNA polymerase theta
Primary source
WormBase:WBGene00020964
Locus tag
CELE_W03A3.2
See related
AllianceGenome:WB:WBGene00020964
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA-directed DNA polymerase activity. Involved in base-excision repair, gap-filling and cellular response to ionizing radiation. Predicted to be located in nucleus. Orthologous to human POLQ (DNA polymerase theta). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

See polq-1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
19
Sequence:
Chromosome: III; NC_003281.10 (5791119..5803160, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene DNA polymerase Neighboring gene Citrate transport protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Homeobox protein ceh-10 Neighboring gene Kinetochore protein Nuf2 homolog Neighboring gene Ras-associating domain-containing protein

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding  
enables DNA binding  
enables DNA-directed DNA polymerase activity  
enables DNA-directed DNA polymerase activity  
enables nucleic acid binding  
Component Evidence Code Pubs
located_in nucleus  

General protein information

Preferred Names
DNA polymerase theta
NP_001367994.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    5791119..5803160 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001379729.2NP_001367994.1  DNA polymerase theta [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0FLQ6, G4SPM6
    Conserved Domains (2) summary
    cd08638
    Location:12301602
    DNA_pol_A_theta; DNA polymerase theta is a low-fidelity family A enzyme implicated in translesion synthesis and in somatic hypermutation
    COG1204
    Location:12696
    BRR2; Replicative superfamily II helicase [Replication, recombination and repair]
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