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Zfp566 zinc finger protein 566 [ Rattus norvegicus (Norway rat) ]

Gene ID: 502316, updated on 4-Jan-2025

Summary

Official Symbol
Zfp566provided by RGD
Official Full Name
zinc finger protein 566provided by RGD
Primary source
RGD:1563239
See related
EnsemblRapid:ENSRNOG00000048138 AllianceGenome:RGD:1563239
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1563239
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF566 (zinc finger protein 566). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Lung (RPKM 39.8), Muscle (RPKM 37.9) and 9 other tissues See more
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Genomic context

See Zfp566 in Genome Data Viewer
Location:
1q21
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (94445850..94461215, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (85318449..85342186, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (88407903..88413209, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 82 Neighboring gene DEAD-box helicase 18 like 1 Neighboring gene small nucleolar RNA SNORA5 Neighboring gene zinc finger protein 260 Neighboring gene zinc finger protein 382

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Clone Names

  • MGC189408

Gene Ontology Provided by RGD

Component Evidence Code Pubs
is_active_in nucleus  

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001134726.1NP_001128198.1  zinc finger protein 566

    See identical proteins and their annotated locations for NP_001128198.1

    Status: PROVISIONAL

    Source sequence(s)
    BC167072
    UniProtKB/TrEMBL
    B2RZ94, M0R4E4
    Related
    ENSRNOP00000064228.4, ENSRNOT00000074582.4
    Conserved Domains (4) summary
    COG5048
    Location:193355
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:225245
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:167189
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:545
    KRAB; KRAB box

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    94445850..94461215 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039088292.2XP_038944220.1  zinc finger protein 566 isoform X2

    Conserved Domains (3) summary
    COG5048
    Location:127289
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:159179
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:101123
    zf-C2H2; Zinc finger, C2H2 type
  2. XM_039088295.2XP_038944223.1  zinc finger protein 566 isoform X2

    Conserved Domains (3) summary
    COG5048
    Location:127289
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:159179
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:101123
    zf-C2H2; Zinc finger, C2H2 type
  3. XM_039088277.2XP_038944205.1  zinc finger protein 566 isoform X1

    UniProtKB/TrEMBL
    B2RZ94, M0R4E4
    Conserved Domains (4) summary
    COG5048
    Location:193355
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:225245
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:167189
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:545
    KRAB; KRAB box
  4. XM_063271859.1XP_063127929.1  zinc finger protein 566 isoform X2

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