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Gimap8 GTPase, IMAP family member 8 [ Rattus norvegicus (Norway rat) ]

Gene ID: 500112, updated on 4-Jan-2025

Summary

Symbol
Gimap8provided by RGD
Full Name
GTPase, IMAP family member 8provided by RGD
Primary source
RGD:1564570
See related
EnsemblRapid:ENSRNOG00000020169 AllianceGenome:RGD:1564570
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
IanT
Summary
Predicted to enable GTP binding activity. Predicted to act upstream of or within regulation of T cell apoptotic process. Predicted to be located in Golgi apparatus; cytosol; and mitochondrion. Predicted to be active in endoplasmic reticulum. Orthologous to human GIMAP8 (GTPase, IMAP family member 8). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Thymus (RPKM 194.6), Lung (RPKM 143.6) and 8 other tissues See more
Orthologs
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Genomic context

See Gimap8 in Genome Data Viewer
Location:
4q24
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (78931003..78942491)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (77600104..77611593)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (78283356..78294838)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 775 Neighboring gene similar to Zinc finger and SCAN domain containing protein 2 (Zinc finger protein 29) Neighboring gene GTPase, IMAP family member 9 Neighboring gene GTPase, IMAP family member 4

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Clone Names

  • MGC116406

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables GTP binding  
Component Evidence Code Pubs
located_in Golgi apparatus  
located_in cytosol  
is_active_in endoplasmic reticulum  
located_in mitochondrion  

General protein information

Preferred Names
GTPase IMAP family member 8
Names
IAN-9
immune-associated nucleotide-binding protein 9
protein IanT

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033923.1NP_001029095.1  GTPase IMAP family member 8

    See identical proteins and their annotated locations for NP_001029095.1

    Status: PROVISIONAL

    Source sequence(s)
    BC099228
    UniProtKB/Swiss-Prot
    Q3LF72, Q4KLG2
    Conserved Domains (2) summary
    cd01852
    Location:49247
    AIG1; AvrRpt2-Induced Gene 1 (AIG1)
    cl38936
    Location:284477
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    78931003..78942491
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039108126.2XP_038964054.1  GTPase IMAP family member 8 isoform X2

    Conserved Domains (2) summary
    cd01852
    Location:77275
    AIG1; AvrRpt2-Induced Gene 1 (AIG1)
    cl38936
    Location:312475
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  2. XM_006236441.5XP_006236503.1  GTPase IMAP family member 8 isoform X1

    UniProtKB/TrEMBL
    A0A0H2UHZ9
    Related
    ENSRNOP00000055946.5, ENSRNOT00000059173.5
    Conserved Domains (2) summary
    cd01852
    Location:77275
    AIG1; AvrRpt2-Induced Gene 1 (AIG1)
    cl21455
    Location:312505
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
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