U.S. flag

An official website of the United States government

Kctd12 potassium channel tetramerization domain containing 12 [ Rattus norvegicus (Norway rat) ]

Gene ID: 364458, updated on 27-Dec-2024

Summary

Symbol
Kctd12provided by RGD
Full Name
potassium channel tetramerization domain containing 12provided by RGD
Primary source
RGD:1309421
See related
EnsemblRapid:ENSRNOG00000066973 AllianceGenome:RGD:1309421
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential; G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential; and identical protein binding activity. Predicted to be involved in regulation of G protein-coupled receptor signaling pathway. Is active in postsynaptic membrane and presynaptic membrane. Orthologous to human KCTD12 (potassium channel tetramerization domain containing 12). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Kctd12 in Genome Data Viewer
Location:
15q21
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (86214786..86220725, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (79800078..79806017, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (87384632..87390627, complement)

Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102546300 Neighboring gene uncharacterized LOC102546379 Neighboring gene uncharacterized LOC134482003 Neighboring gene uncharacterized LOC120097063 Neighboring gene aconitate decarboxylase 1

Genomic regions, transcripts, and products

Interactions

General gene information

Gene Ontology Provided by RGD

Component Evidence Code Pubs
is_active_in GABA-ergic synapse  
is_active_in postsynaptic membrane  
is_active_in postsynaptic membrane PubMed 
is_active_in postsynaptic membrane  
located_in postsynaptic membrane  
is_active_in presynaptic active zone membrane  
is_active_in presynaptic membrane  
is_active_in presynaptic membrane PubMed 
is_active_in presynaptic membrane  
located_in presynaptic membrane  
part_of receptor complex  
part_of receptor complex  

General protein information

Preferred Names
BTB/POZ domain-containing protein KCTD12
Names
potassium channel tetramerisation domain containing 12

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001399515.1NP_001386444.1  BTB/POZ domain-containing protein KCTD12

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000015
    UniProtKB/TrEMBL
    A0A8I5Y7I2, A6HU83
    Related
    ENSRNOP00000077409.2, ENSRNOT00000110749.2
    Conserved Domains (2) summary
    cd18397
    Location:32131
    BTB_POZ_KCTD12_Pfetin; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium channel tetramerization domain-containing protein 12 (KCTD12)
    cd22217
    Location:208327
    H1_KCTD12; H1 domain found in potassium channel tetramerization domain-containing protein 12

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086033.1 Reference GRCr8

    Range
    86214786..86220725 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
External link. Please review our privacy policy.