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ASPGA1 N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 830704, updated on 18-Sep-2024

Summary

Official Symbol
ASPGA1
Official Full Name
N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein
Primary source
TAIR:AT5G08100
Locus tag
AT5G08100
See related
Araport:AT5G08100
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
asparaginase A1; T22D6.40; T22D6_40
Summary
Encodes an asparaginase that catalyzes the degradation of L-asparagine to L-aspartic acid and ammonia.
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Genomic context

See ASPGA1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
4
Sequence:
Chromosome: 5; NC_003076.8 (2592976..2594701, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene syntaxin of plants 132 Neighboring gene uncharacterized protein Neighboring gene UBQ, helicase-c and DEAD-like helicase domain-containing protein Neighboring gene movement protein binding protein 2C

Genomic regions, transcripts, and products

Genomic Sequence:
NC_003076.8

Pathways from PubChem

General gene information

NM_120892.4
NM_203020.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables asparaginase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables beta-aspartyl-peptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
 
located_in plasma membrane HDA PubMed 

General protein information

Preferred Names
N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein
NP_196427.1
  • N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein; CONTAINS InterPro DOMAIN/s: Peptidase T2, asparaginase 2 (InterPro:IPR000246); BEST Arabidopsis thaliana protein match is: N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein (TAIR:AT3G16150.1); Has 3243 Blast hits to 3196 proteins in 873 species: Archae - 113; Bacteria - 1502; Metazoa - 516; Fungi - 215; Plants - 193; Viruses - 0; Other Eukaryotes - 704 (source: NCBI BLink).
NP_974749.1
  • N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein; CONTAINS InterPro DOMAIN/s: Peptidase T2, asparaginase 2 (InterPro:IPR000246); BEST Arabidopsis thaliana protein match is: N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein (TAIR:AT3G16150.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    2592976..2594701 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_120892.4NP_196427.1  N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_196427.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P50287, Q9LEZ6
    UniProtKB/TrEMBL
    A0A178UF74
    Conserved Domains (2) summary
    PRK10226
    Location:1299
    PRK10226; isoaspartyl peptidase; Provisional
    PLN02689
    Location:1313
    PLN02689; Bifunctional isoaspartyl peptidase/L-asparaginase
  2. NM_203020.2NP_974749.1  N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_974749.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4K9K7
    Conserved Domains (1) summary
    PLN02689
    Location:1233
    PLN02689; Bifunctional isoaspartyl peptidase/L-asparaginase