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CG7059 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42626, updated on 4-Jan-2025

Summary

Official Symbol
CG7059provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0038957
Locus tag
Dmel_CG7059
See related
AllianceGenome:FB:FBgn0038957
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG7059
Summary
Predicted to enable 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity and bisphosphoglycerate mutase activity. Predicted to be involved in canonical glycolysis and gluconeogenesis. Predicted to be active in cytosol. Is expressed in eye. Human ortholog(s) of this gene implicated in myoglobinuria. Orthologous to human PGAM1 (phosphoglycerate mutase 1); PGAM2 (phosphoglycerate mutase 2); and PGAM4 (phosphoglycerate mutase family member 4). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See CG7059 in Genome Data Viewer
Location:
94A11-94A11; 3-74 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (22389780..22392349)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (18215502..18218071)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Glycerol-3-phosphate dehydrogenase 3 Neighboring gene Carbonic anhydrase 8 Neighboring gene uncharacterized protein Neighboring gene transfer RNA:Serine-GCT 2-3 Neighboring gene transfer RNA:Serine-GCT 2-4

Genomic regions, transcripts, and products

Interactions

General gene information

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in canonical glycolysis  
involved_in gluconeogenesis  
involved_in glycolytic process  
Component Evidence Code Pubs
is_active_in cytosol  

General protein information

Preferred Names
uncharacterized protein
Names
CG7059-PA
CG7059-PC
CG7059-PD
NP_651034.2
NP_732730.1
NP_788713.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    22389780..22392349
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142777.2 → NP_651034.2  uncharacterized protein Dmel_CG7059, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651034.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T8W6, Q9VD18
    Related
    FBpp0083616
    Conserved Domains (1) summary
    cl11399
    Location:19 → 266
    HP; Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction
  2. NM_176536.2 → NP_788713.1  uncharacterized protein Dmel_CG7059, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_788713.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q86BN6
    Related
    FBpp0083618
    Conserved Domains (1) summary
    cl11399
    Location:14 → 261
    HP; Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction
  3. NM_170008.2 → NP_732730.1  uncharacterized protein Dmel_CG7059, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_732730.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q86BN5
    Related
    FBpp0083617
    Conserved Domains (1) summary
    cl11399
    Location:5 → 252
    HP; Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction
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