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    CRSH Ca2+-activated RelA/spot-like protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821012, updated on 18-Sep-2024

    Summary

    Official Symbol
    CRSH
    Official Full Name
    Ca2+-activated RelA/spot-like protein
    Primary source
    TAIR:AT3G17470
    Locus tag
    AT3G17470
    See related
    Araport:AT3G17470
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATCRSH; Ca2+-activated RelA/spot homolog
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    Genomic context

    See CRSH in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    4
    Sequence:
    Chromosome: 3; NC_003074.8 (5979814..5982145)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene hAT dimerization domain-containing protein Neighboring gene PHD finger family protein Neighboring gene ribosomal protein L3 plastid Neighboring gene F-box/associated interaction domain protein Neighboring gene F-box and associated interaction domains-containing protein

    General gene information

    NM_112627.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GTP diphosphokinase activity  
    enables GTP diphosphokinase activity PubMed 
    enables calcium ion binding  
    Component Evidence Code Pubs
    located_in chloroplast PubMed 
    located_in chloroplast  
    located_in mitochondrion  

    General protein information

    Preferred Names
    Ca2+-activated RelA/spot-like protein
    NP_188374.2
    • Ca2+-activated RelA/spot homolog (CRSH); FUNCTIONS IN: GTP diphosphokinase activity, calcium ion binding; INVOLVED IN: guanosine tetraphosphate metabolic process; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: EF-Hand 1, calcium-binding site (InterPro:IPR018247), EF-HAND 2 (InterPro:IPR018249), EF-hand-like domain (InterPro:IPR011992), Calcium-binding EF-hand (InterPro:IPR002048), EF-hand (InterPro:IPR018248), RelA/SpoT (InterPro:IPR007685); BEST Arabidopsis thaliana protein match is: RELA/SPOT homolog 3 (TAIR:AT1G54130.1); Has 14021 Blast hits to 13962 proteins in 3173 species: Archae - 6; Bacteria - 8120; Metazoa - 1259; Fungi - 992; Plants - 727; Viruses - 0; Other Eukaryotes - 2917 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      5979814..5982145
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001338291.1NP_001327079.1  Ca2+-activated RelA/spot-like protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V9Z0, A0A1I9LR76, A0A5S9XDD3, A0A654F855
    2. NM_001338292.1NP_001327078.1  Ca2+-activated RelA/spot-like protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LR75
    3. NM_112627.4NP_188374.2  Ca2+-activated RelA/spot-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_188374.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q84R11, Q9LUQ0
      UniProtKB/TrEMBL
      A0A178V9Z0, A0A5S9XDD3, A0A654F855
      Conserved Domains (5) summary
      COG0317
      Location:121441
      SpoT; (p)ppGpp synthase/hydrolase, HD superfamily [Signal transduction mechanisms, Transcription]
      pfam04607
      Location:309432
      RelA_SpoT; Region found in RelA / SpoT proteins
      pfam13499
      Location:477529
      EF-hand_7; EF-hand domain pair
      cl08302
      Location:477529
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cl21469
      Location:108242
      HDc; Metal dependent phosphohydrolases with conserved 'HD' motif
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