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CG34393 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33534, updated on 4-Jan-2025

Summary

Official Symbol
CG34393provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0085422
Locus tag
Dmel_CG34393
See related
AllianceGenome:FB:FBgn0085422
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG15405; CG8829; Dmel\CG34393; Dm_2L:14421
Old locus tag
CG15405; CG8829; Dmel_CG15405; Dmel_CG8829
Summary
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in Ras protein signal transduction and positive regulation of Ras protein signal transduction. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See CG34393 in Genome Data Viewer
Location:
23D4-23D5; 2-8 cM
Exon count:
14
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (3175112..3200496, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (3175112..3200496, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45336 Neighboring gene long non-coding RNA:CR45337

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity  
enables guanyl-nucleotide exchange factor activity  
enables guanyl-nucleotide exchange factor activity  
Component Evidence Code Pubs
is_active_in plasma membrane  

General protein information

Preferred Names
uncharacterized protein
Names
CG34393-PA
CG34393-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    3175112..3200496 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_134909.3NP_608753.2  uncharacterized protein Dmel_CG34393, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608753.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VQM8
    Conserved Domains (2) summary
    cd06224
    Location:196300
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    pfam00617
    Location:334473
    RasGEF; RasGEF domain
  2. NM_001298649.1NP_001285578.1  uncharacterized protein Dmel_CG34393, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285578.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VQM8
    Conserved Domains (2) summary
    cd06224
    Location:196300
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    pfam00617
    Location:334473
    RasGEF; RasGEF domain
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