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    CG12379 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32512, updated on 4-Jan-2025

    Summary

    Official Symbol
    CG12379provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030676
    Locus tag
    Dmel_CG12379
    See related
    AllianceGenome:FB:FBgn0030676
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG12379
    Summary
    Predicted to enable protein folding chaperone and protein-folding chaperone binding activity. Predicted to be involved in several processes, including chaperone-mediated protein complex assembly; protein import into mitochondrial matrix; and protein stabilization. Predicted to be located in mitochondrial matrix. Predicted to be active in cytosol; mitochondrion; and nucleus. Orthologous to human DNLZ (DNL-type zinc finger). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
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    Genomic context

    See CG12379 in Genome Data Viewer
    Location:
    13E12-13E12; 1-51 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (15733222..15733996, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (15627255..15628029, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 Neighboring gene uncharacterized protein Neighboring gene Magnetic receptor Neighboring gene Actin-related protein 6 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein folding chaperone  
    enables protein-folding chaperone binding  
    enables zinc ion binding  
    Process Evidence Code Pubs
    involved_in chaperone-mediated protein complex assembly  
    involved_in protein folding  
    involved_in protein import into mitochondrial matrix  
    involved_in protein import into mitochondrial matrix  
    involved_in protein stabilization  
    Component Evidence Code Pubs
    is_active_in cytosol  
    located_in mitochondrial matrix  
    is_active_in mitochondrion  
    is_active_in mitochondrion  
    is_active_in nucleus  

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG12379-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      15733222..15733996 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132833.3NP_573061.2  uncharacterized protein Dmel_CG12379 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_573061.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6NMW4, Q9VXR1
      Conserved Domains (1) summary
      pfam05180
      Location:93158
      zf-DNL; DNL zinc finger
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