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scpl-4 Mitochondrial import inner membrane translocase subunit TIM50 [ Caenorhabditis elegans ]

Gene ID: 179481, updated on 4-Jan-2025

Summary

Official Symbol
scpl-4
Official Full Name
Mitochondrial import inner membrane translocase subunit TIM50
Primary source
WormBase:WBGene00011897
Locus tag
CELE_T21C9.12
See related
AllianceGenome:WB:WBGene00011897
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in protein import into mitochondrial matrix. Predicted to be located in mitochondrial inner membrane. Predicted to be part of TIM23 mitochondrial import inner membrane translocase complex. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 9. Orthologous to human TIMM50 (translocase of inner mitochondrial membrane 50). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

See scpl-4 in Genome Data Viewer
Location:
chromosome: V
Exon count:
8
Sequence:
Chromosome: V; NC_003283.11 (10599104..10602146)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene DUF4149 domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene glutaminyl-peptide cyclotransferase

Interactions

General gene information

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in protein import into mitochondrial matrix  
involved_in protein transport  
Component Evidence Code Pubs
part_of TIM23 mitochondrial import inner membrane translocase complex  
part_of TIM23 mitochondrial import inner membrane translocase complex  
located_in membrane  
located_in mitochondrial inner membrane  
located_in mitochondrion  

General protein information

Preferred Names
Mitochondrial import inner membrane translocase subunit TIM50
NP_001360575.1
  • Confirmed by transcript evidence
NP_505722.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    10599104..10602146
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001373099.3NP_001360575.1  Mitochondrial import inner membrane translocase subunit TIM50 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A486WU22
    Conserved Domains (1) summary
    pfam03031
    Location:247395
    NIF; NLI interacting factor-like phosphatase
  2. NM_073321.7NP_505722.1  Mitochondrial import inner membrane translocase subunit TIM50 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_505722.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q22647
    Conserved Domains (1) summary
    pfam03031
    Location:248396
    NIF; NLI interacting factor-like phosphatase
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