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Syt14 Synaptotagmin 14 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40544, updated on 4-Jan-2025

Summary

Official Symbol
Syt14provided by FlyBase
Official Full Name
Synaptotagmin 14provided by FlyBase
Primary source
FLYBASE:FBgn0261086
Locus tag
Dmel_CG9778
See related
AllianceGenome:FB:FBgn0261086
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG9778; Dmel\CG9778; dsyt14; Syt 14; syt14; SYT14; syt16; Syt16
Summary
Predicted to enable phospholipid binding activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 11. Orthologous to several human genes including SYT16 (synaptotagmin 16). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See Syt14 in Genome Data Viewer
Location:
82A3-82A3; 3-47.1 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (4314455..4319069, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (140177..144791, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR46140 Neighboring gene Vacuolar protein sorting 24 Neighboring gene Melanization Protease 1 Neighboring gene Suv3 helicase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Interactions

General gene information

mobile_element

  • Loc: c4314530-4314503 mobile_element_type = transposon:1360{}3731

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables phospholipid binding  
enables phospholipid binding PubMed 
Component Evidence Code Pubs
located_in membrane  

General protein information

Preferred Names
synaptotagmin 14
Names
CG9778-PA
CG9778-PC
CG9778-PD
Syt14-PA
Syt14-PC
Syt14-PD
syt14

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    4314455..4319069 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001275321.1 → NP_001262250.1  synaptotagmin 14, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262250.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VN04
    Conserved Domains (2) summary
    cd08389
    Location:291 → 413
    C2A_Synaptotagmin-14_16; C2A domain first repeat present in Synaptotagmins 14 and 16
    cd08408
    Location:446 → 584
    C2B_Synaptotagmin-14_16; C2 domain second repeat present in Synaptotagmins 14 and 16
  2. NM_001275320.1 → NP_001262249.1  synaptotagmin 14, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262249.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4KF61
    Conserved Domains (2) summary
    cd08389
    Location:291 → 413
    C2A_Synaptotagmin-14_16; C2A domain first repeat present in Synaptotagmins 14 and 16
    cd08408
    Location:446 → 584
    C2B_Synaptotagmin-14_16; C2 domain second repeat present in Synaptotagmins 14 and 16
  3. NM_141196.2 → NP_649453.1  synaptotagmin 14, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649453.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VN04
    Related
    FBpp0078597
    Conserved Domains (2) summary
    cd08389
    Location:291 → 413
    C2A_Synaptotagmin-14_16; C2A domain first repeat present in Synaptotagmins 14 and 16
    cd08408
    Location:446 → 584
    C2B_Synaptotagmin-14_16; C2 domain second repeat present in Synaptotagmins 14 and 16
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