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MAP9 microtubule associated protein 9 [ Homo sapiens (human) ]

Gene ID: 79884, updated on 10-Dec-2024

Summary

Official Symbol
MAP9provided by HGNC
Official Full Name
microtubule associated protein 9provided by HGNC
Primary source
HGNC:HGNC:26118
See related
Ensembl:ENSG00000164114 MIM:610070; AllianceGenome:HGNC:26118
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ASAP
Summary
ASAP is a microtubule-associated protein required for spindle function, mitotic progression, and cytokinesis (Saffin et al., 2005 [PubMed 16049101]).[supplied by OMIM, Mar 2008]
Expression
Broad expression in brain (RPKM 7.7), thyroid (RPKM 7.3) and 23 other tissues See more
Orthologs
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Genomic context

See MAP9 in Genome Data Viewer
Location:
4q32.1
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (155342658..155376965, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (158674560..158709763, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (156263810..156298117, complement)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene neuropeptide Y receptor Y2 Neighboring gene NPY2R antisense RNA 1 Neighboring gene uncharacterized LOC105377502 Neighboring gene MAP9 antisense RNA 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22081 Neighboring gene TBC1 domain family member 3C pseudogene Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon pseudogene 4

Genomic regions, transcripts, and products

Expression

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

General gene information

Clone Names

  • FLJ21159

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables microtubule binding  
enables microtubule binding PubMed 
Component Evidence Code Pubs
is_active_in astral microtubule  
located_in astral microtubule PubMed 
located_in axon  
located_in cytoplasm PubMed 
located_in mitotic spindle PubMed 
located_in mitotic spindle midzone  
located_in spindle midzone PubMed 

General protein information

Preferred Names
microtubule-associated protein 9
Names
aster-associated protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039580.2NP_001034669.1  microtubule-associated protein 9

    See identical proteins and their annotated locations for NP_001034669.1

    Status: VALIDATED

    Source sequence(s)
    AC097467, AY690636, BC022852, CF144347
    Consensus CDS
    CCDS35493.1
    UniProtKB/Swiss-Prot
    Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6
    UniProtKB/TrEMBL
    B9EJB6
    Related
    ENSP00000310593.4, ENST00000311277.9
    Conserved Domains (1) summary
    cl01868
    Location:521597
    YukC; WXG100 protein secretion system (Wss), protein YukC

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

    Range
    155342658..155376965 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011532255.4XP_011530557.1  microtubule-associated protein 9 isoform X3

    UniProtKB/TrEMBL
    B9EJB6
    Conserved Domains (1) summary
    cl01868
    Location:449525
    YukC; WXG100 protein secretion system (Wss), protein YukC
  2. XM_011532254.2XP_011530556.1  microtubule-associated protein 9 isoform X1

    See identical proteins and their annotated locations for XP_011530556.1

    UniProtKB/Swiss-Prot
    Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6
    UniProtKB/TrEMBL
    B9EJB6
    Conserved Domains (1) summary
    cl01868
    Location:521597
    YukC; WXG100 protein secretion system (Wss), protein YukC
  3. XM_017008616.2XP_016864105.1  microtubule-associated protein 9 isoform X2

    UniProtKB/TrEMBL
    B9EJB6
    Conserved Domains (2) summary
    PTZ00121
    Location:280620
    PTZ00121; MAEBL; Provisional
    PRK12704
    Location:506591
    PRK12704; phosphodiesterase; Provisional
  4. XM_011532253.2XP_011530555.1  microtubule-associated protein 9 isoform X1

    See identical proteins and their annotated locations for XP_011530555.1

    UniProtKB/Swiss-Prot
    Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6
    UniProtKB/TrEMBL
    B9EJB6
    Conserved Domains (1) summary
    cl01868
    Location:521597
    YukC; WXG100 protein secretion system (Wss), protein YukC
  5. XM_017008617.2XP_016864106.1  microtubule-associated protein 9 isoform X2

    UniProtKB/TrEMBL
    B9EJB6
    Conserved Domains (2) summary
    PTZ00121
    Location:280620
    PTZ00121; MAEBL; Provisional
    PRK12704
    Location:506591
    PRK12704; phosphodiesterase; Provisional

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060928.1 Alternate T2T-CHM13v2.0

    Range
    158674560..158709763 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054350850.1XP_054206825.1  microtubule-associated protein 9 isoform X3

    UniProtKB/TrEMBL
    B9EJB6
  2. XM_054350847.1XP_054206822.1  microtubule-associated protein 9 isoform X1

    UniProtKB/Swiss-Prot
    Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6
    UniProtKB/TrEMBL
    B9EJB6
  3. XM_054350848.1XP_054206823.1  microtubule-associated protein 9 isoform X2

    UniProtKB/TrEMBL
    B9EJB6
  4. XM_054350846.1XP_054206821.1  microtubule-associated protein 9 isoform X1

    UniProtKB/Swiss-Prot
    Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6
    UniProtKB/TrEMBL
    B9EJB6
  5. XM_054350849.1XP_054206824.1  microtubule-associated protein 9 isoform X2

    UniProtKB/TrEMBL
    B9EJB6

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