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Psg23 pregnancy-specific beta-1-glycoprotein 23 [ Mus musculus (house mouse) ]

Gene ID: 56868, updated on 9-Dec-2024

Summary

Official Symbol
Psg23provided by MGI
Official Full Name
pregnancy-specific beta-1-glycoprotein 23provided by MGI
Primary source
MGI:MGI:1891355
See related
Ensembl:ENSMUSG00000074359 AllianceGenome:MGI:1891355
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
cea11; 1620401C02Rik
Summary
Enables heparan sulfate proteoglycan binding activity. Acts upstream of or within negative regulation of blood coagulation and positive regulation of gene expression. Predicted to be located in apical plasma membrane and cytosol. Predicted to be active in external side of plasma membrane. Orthologous to human CEACAM7 (CEA cell adhesion molecule 7). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Restricted expression toward placenta adult (RPKM 131.2) See more
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Genomic context

See Psg23 in Genome Data Viewer
Location:
7 A3; 7 9.18 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (18340268..18350426, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (18606343..18616501, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene pregnancy-specific beta-1-glycoprotein 27 Neighboring gene STARR-seq mESC enhancer starr_18171 Neighboring gene RNA (guanine-9-) methyltransferase domain containing 2 pseudogene Neighboring gene RNA (guanine-9-) methyltransferase domain containing 2 pseudogene Neighboring gene pregnancy-specific beta-1-glycoprotein 21

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Spontaneous (1)  1 citation

General gene information

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in apical plasma membrane  
is_active_in cellular_component  
located_in cytosol  
is_active_in external side of plasma membrane  
located_in plasma membrane  

General protein information

Preferred Names
pregnancy-specific glycoprotein 23

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_020261.4NP_064657.2  pregnancy-specific glycoprotein 23

    See identical proteins and their annotated locations for NP_064657.2

    Status: VALIDATED

    Source sequence(s)
    AC165084, AK018828
    Consensus CDS
    CCDS20874.1
    UniProtKB/TrEMBL
    Q9D2U0, Q9R1F9
    Related
    ENSMUSP00000056586.7, ENSMUST00000057810.7
    Conserved Domains (3) summary
    cd05774
    Location:155259
    Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
    smart00408
    Location:396457
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:388468
    IG_like; Immunoglobulin like

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    18340268..18350426 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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