U.S. flag

An official website of the United States government

krt17 keratin 17 [ Danio rerio (zebrafish) ]

Gene ID: 100034647, updated on 9-Dec-2024

Summary

Official Symbol
krt17provided by ZNC
Official Full Name
keratin 17provided by ZNC
Primary source
ZFIN:ZDB-GENE-060503-86
See related
Ensembl:ENSDARG00000094041 AllianceGenome:ZFIN:ZDB-GENE-060503-86
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkeyp-113d7.7
Summary
Predicted to enable structural molecule activity. Acts upstream of or within fin regeneration. Predicted to be located in intermediate filament. Predicted to be active in cytoskeleton. Is expressed in EVL; eye; and trunk. Human ortholog(s) of this gene implicated in several diseases, including corneal dystrophy (multiple); ectodermal dysplasia (multiple); epidermolytic hyperkeratosis (multiple); focal nonepidermolytic palmoplantar keratoderma 1; and pachyonychia congenita. Orthologous to several human genes including KRT13 (keratin 13); KRT14 (keratin 14); and KRT15 (keratin 15). [provided by Alliance of Genome Resources, Dec 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See krt17 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (5367425..5369465, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (5450939..5452979, complement)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene type I cytokeratin, enveloping layer, like Neighboring gene type I cytokeratin, enveloping layer Neighboring gene keratin 91 Neighboring gene eukaryotic translation initiation factor 1

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
is_active_in cytoskeleton  
located_in intermediate filament  

General protein information

Preferred Names
keratin, type I cytoskeletal 17

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001083105.1NP_001076574.1  keratin, type I cytoskeletal 17

    See identical proteins and their annotated locations for NP_001076574.1

    Status: PROVISIONAL

    Source sequence(s)
    BX323079
    UniProtKB/TrEMBL
    A8E594, Q1LXJ1
    Related
    ENSDARP00000095774.5, ENSDART00000105004.7
    Conserved Domains (1) summary
    pfam00038
    Location:72380
    Filament; Intermediate filament protein

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    5367425..5369465 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
External link. Please review our privacy policy.