U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    Slc38a8 solute carrier family 38, member 8 [ Mus musculus (house mouse) ]

    Gene ID: 234788, updated on 9-Dec-2024

    Summary

    Official Symbol
    Slc38a8provided by MGI
    Official Full Name
    solute carrier family 38, member 8provided by MGI
    Primary source
    MGI:MGI:2685433
    See related
    Ensembl:ENSMUSG00000034224 AllianceGenome:MGI:2685433
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm587
    Summary
    Predicted to enable L-amino acid transmembrane transporter activity. Acts upstream of or within nervous system development; retinal pigment epithelium development; and visual perception. Predicted to be located in axon and cell cortex. Predicted to be active in membrane. Used to study foveal hypoplasia 2. Human ortholog(s) of this gene implicated in foveal hypoplasia 2. Orthologous to human SLC38A8 (solute carrier family 38 member 8). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Slc38a8 in Genome Data Viewer
    Location:
    8 E1; 8 67.8 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (120206313..120228503, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (119479574..119501698, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene oxidative stress induced growth inhibitor 1 Neighboring gene N-terminal EF-hand calcium binding protein 2 Neighboring gene predicted gene, 53462 Neighboring gene STARR-seq mESC enhancer starr_22850 Neighboring gene membrane-bound transcription factor peptidase, site 1 Neighboring gene STARR-seq mESC enhancer starr_22853 Neighboring gene STARR-positive B cell enhancer mm9_chr8:122082621-122082922 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:122087691-122087878 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:122087910-122088232 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:122093859-122094132 Neighboring gene hydroxysteroid dehydrogenase like 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (6)  1 citation
    • Gene trapped (1) 

    General gene information

    Clone Names

    • MGC113805

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in axon  
    located_in cell cortex  
    is_active_in cellular_component  
    is_active_in membrane  
    located_in membrane  

    General protein information

    Preferred Names
    solute carrier family 38 member 8
    Names
    amino acid transporter SLC38A8
    putative sodium-coupled neutral amino acid transporter 8

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009950.2NP_001009950.1  solute carrier family 38 member 8

      See identical proteins and their annotated locations for NP_001009950.1

      Status: VALIDATED

      Source sequence(s)
      AC140672, AC166781
      Consensus CDS
      CCDS22706.1
      UniProtKB/Swiss-Prot
      Q5HZH7
      Related
      ENSMUSP00000038438.9, ENSMUST00000036748.15
      Conserved Domains (2) summary
      COG0814
      Location:23429
      SdaC; Amino acid permease [Amino acid transport and metabolism]
      cl00456
      Location:23421
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      120206313..120228503 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011248368.2XP_011246670.1  solute carrier family 38 member 8 isoform X1

      See identical proteins and their annotated locations for XP_011246670.1

      Conserved Domains (1) summary
      cl00456
      Location:1322
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
    Loading
    External link. Please review our privacy policy.