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LOC126806844 MED14-independent group 3 enhancer GRCh37_chr3:150025558-150026757 [ Homo sapiens (human) ]

Gene ID: 126806844, updated on 12-Sep-2024

Summary

Gene symbol
LOC126806844
Gene description
MED14-independent group 3 enhancer GRCh37_chr3:150025558-150026757
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the STARR-seq (self-transcribing active regulatory region sequencing) massively parallel reporter assay in HCT116 colorectal carcinoma cells. This sequence was defined as a group 3 enhancer that depends on the BRD2, BRD4, P300/CBP and CDK7 cofactors, but it has limited or no dependence on the MED14 core Mediator complex subunit. [provided by RefSeq, Sep 2022]
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Genomic context

See LOC126806844 in Genome Data Viewer
Location:
chromosome: 3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (150307771..150308970)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (153059040..153060239)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (150025558..150026757)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124906376 Neighboring gene long intergenic non-protein coding RNA 1214 Neighboring gene uncharacterized LOC105374154 Neighboring gene uncharacterized LOC107986141 Neighboring gene uncharacterized LOC107986142 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr3:150087822-150088690 Neighboring gene Sharpr-MPRA regulatory region 6181 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20684 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_65240 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20685 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14814 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20686 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14815 Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:150127902-150128781 Neighboring gene TSC22 domain family member 2 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_65259

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_083164.1 

    Range
    101..1300
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    150307771..150308970
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    153059040..153060239
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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