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CSAG1 chondrosarcoma associated gene 1 [ Homo sapiens (human) ]

Gene ID: 158511, updated on 10-Dec-2024

Summary

Official Symbol
CSAG1provided by HGNC
Official Full Name
chondrosarcoma associated gene 1provided by HGNC
Primary source
HGNC:HGNC:24294
See related
Ensembl:ENSG00000198930 MIM:300944; AllianceGenome:HGNC:24294
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CSAGE; CT24.1
Summary
This gene encodes a member of a family of tumor antigens. The protein is expressed in chondrosarcomas, but may also be expressed in normal tissues such as testis. Alternative splicing of this gene results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See CSAG1 in Genome Data Viewer
Location:
Xq28
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (152727484..152733721, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (150994063..151000300, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (151903242..151909518)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124905224 Neighboring gene MAGE family member A2B Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chrX:151902449-151903648 Neighboring gene MAGE family member A12 Neighboring gene CSAG family member 4 (pseudogene) Neighboring gene MAGE family member A2

Genomic regions, transcripts, and products

Expression

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Interactions

General gene information

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in centrosome PubMed 
located_in cytoplasm  
located_in spindle pole PubMed 

General protein information

Preferred Names
chondrosarcoma-associated gene 1 protein
Names
cancer/testis antigen 24.1
cancer/testis antigen CSAGE
cancer/testis antigen family 24, member 1
putative chondrosarcoma-associated gene 1 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_013228.2 RefSeqGene

    Range
    5014..11251
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001102576.3NP_001096046.2  chondrosarcoma-associated gene 1 protein

    See identical proteins and their annotated locations for NP_001096046.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (c) differs in the 5' UTR compared to variant a. Variants a and c both encode the same protein.
    Source sequence(s)
    AF195880, BC059947
    Consensus CDS
    CCDS76047.1
    UniProtKB/Swiss-Prot
    A0A024RC18, A6NE22, Q6PB30
    UniProtKB/TrEMBL
    A0AAG2UXQ3
    Related
    ENSP00000396520.2, ENST00000452779.3
  2. NM_153478.3NP_705611.2  chondrosarcoma-associated gene 1 protein

    See identical proteins and their annotated locations for NP_705611.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (a) represents the longer transcript. Variants a and c both encode the same protein.
    Source sequence(s)
    AF195880, AF268419, BC059947
    Consensus CDS
    CCDS76047.1
    UniProtKB/Swiss-Prot
    A0A024RC18, A6NE22, Q6PB30
    UniProtKB/TrEMBL
    A0AAG2UXQ3
    Related
    ENSP00000359310.3, ENST00000370287.7

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    152727484..152733721 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047441858.1XP_047297814.1  chondrosarcoma-associated gene 1 protein isoform X1

    UniProtKB/TrEMBL
    A0AAG2UXQ3
  2. XM_047441859.1XP_047297815.1  chondrosarcoma-associated gene 1 protein isoform X1

    UniProtKB/TrEMBL
    A0AAG2UXQ3

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_025791818.1 Reference GRCh38.p14 PATCHES

    Range
    349888..356164
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054333335.1XP_054189310.1  chondrosarcoma-associated gene 1 protein isoform X1

    UniProtKB/TrEMBL
    A0AAG2UXQ3
  2. XM_054333336.1XP_054189311.1  chondrosarcoma-associated gene 1 protein isoform X1

    UniProtKB/TrEMBL
    A0AAG2UXQ3

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    150994063..151000300 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

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