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Cyt-c1 Cytochrome c1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38612, updated on 27-Dec-2024

Summary

Official Symbol
Cyt-c1provided by FlyBase
Official Full Name
Cytochrome c1provided by FlyBase
Primary source
FLYBASE:FBgn0035600
Locus tag
Dmel_CG4769
See related
AllianceGenome:FB:FBgn0035600
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-EST:Posey141; CG4769; CY1; Cyc1; Dmel\CG4769
Summary
Predicted to enable ubiquinol-cytochrome-c reductase activity. Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Located in mitochondrion. Is expressed in several structures, including Malpighian tubule primordium; adult head; embryonic/larval midgut primordium; gut section; and larval muscle cell. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 6. Orthologous to human CYC1 (cytochrome c1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See Cyt-c1 in Genome Data Viewer
Location:
64C13-64C13; 3-13 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (5360211..5362798)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (5353311..5355898)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene transfer RNA:Valine-TAC 1-2 Neighboring gene Kinesin-like protein at 64D Neighboring gene Ubiquitin-conjugating enzyme variant 1A Neighboring gene membrin Neighboring gene Prefoldin 4

Genomic regions, transcripts, and products

Interactions

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables electron transfer activity  
enables heme binding  
enables ubiquinol-cytochrome-c reductase activity  
Component Evidence Code Pubs
located_in mitochondrial inner membrane  
located_in mitochondrion PubMed 
part_of respiratory chain complex III  
part_of respiratory chain complex III  

General protein information

Preferred Names
cytochrome c1
Names
CG4769-PA
CG4769-PB
Cyt-c1-PA
Cyt-c1-PB
Cytochrome-c-1
Ubiquinol-cytochrome c oxidoreductase cytochrome C1
Ubiquinol-cytochrome c reductase cytochrome C1, heme protein
cytochrome c-1
cytochrome c1, heme protein, mitochondrial
NP_001246637.1
NP_647958.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    5360211..5362798
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_139701.2 → NP_647958.1  cytochrome c1, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_647958.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VRL0
    Related
    FBpp0076848
    Conserved Domains (2) summary
    COG2857
    Location:69 → 296
    CYT1; Cytochrome c1 [Energy production and conversion]
    pfam02167
    Location:77 → 295
    Cytochrom_C1; Cytochrome C1 family
  2. NM_001259708.2 → NP_001246637.1  cytochrome c1, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246637.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VRL0
    Conserved Domains (2) summary
    COG2857
    Location:69 → 296
    CYT1; Cytochrome c1 [Energy production and conversion]
    pfam02167
    Location:77 → 295
    Cytochrom_C1; Cytochrome C1 family
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