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S-Lap5 Sperm-Leucylaminopeptidase 5 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36515, updated on 27-Dec-2024

Summary

Official Symbol
S-Lap5provided by FlyBase
Official Full Name
Sperm-Leucylaminopeptidase 5provided by FlyBase
Primary source
FLYBASE:FBgn0033860
Locus tag
Dmel_CG18369
See related
AllianceGenome:FB:FBgn0033860
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG18369; Dmel\CG18369; S-LAP 5
Summary
Predicted to enable manganese ion binding activity. Involved in mesoderm development. Predicted to be located in major mitochondrial derivative. Predicted to be active in cytoplasm. Is expressed in adult head; spermatogonium; spermatozoon; and testis. Orthologous to human LAP3 (leucine aminopeptidase 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See S-Lap5 in Genome Data Viewer
Location:
50B4-50B5; 2-68 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (13596677..13598750)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (9484182..9486255)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene fandango Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Interactions

General gene information

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in mesoderm development PubMed 
involved_in proteolysis  
Component Evidence Code Pubs
is_active_in cytoplasm  
located_in cytoplasm  
located_in major mitochondrial derivative  

General protein information

Preferred Names
Sperm-Leucylaminopeptidase 5
Names
CG18369-PA
S-Lap5-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    13596677..13598750
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_137048.2NP_610892.1  Sperm-Leucylaminopeptidase 5 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610892.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z9G3, Q8T4F1
    Related
    FBpp0086750, FBtr0087624
    Conserved Domains (2) summary
    COG0260
    Location:83544
    PepB; Leucyl aminopeptidase [Amino acid transport and metabolism]
    cd00433
    Location:60540
    Peptidase_M17; Cytosol aminopeptidase family, N-terminal and catalytic domains. Family M17 contains zinc- and manganese-dependent exopeptidases ( EC 3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and ...
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