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LRRK1 leucine rich repeat kinase 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 694358, updated on 17-Aug-2024

Summary

Official Symbol
LRRK1provided by VGNC
Official Full Name
leucine rich repeat kinase 1provided by VGNC
Primary source
VGNC:VGNC:81446
See related
Ensembl:ENSMMUG00000013325
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
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Genomic context

See LRRK1 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
37
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (80209241..80363268)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (79685163..79838679)

Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene gastric cancer associated WDR5 and KAT2A binding lncRNA Neighboring gene aldehyde dehydrogenase 1 family member A3 Neighboring gene uncharacterized LOC114679519 Neighboring gene chondroitin sulfate synthase 1 Neighboring gene selenoprotein S

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding PubMed 
enables protein binding PubMed 
enables protein kinase activity PubMed 

General protein information

Preferred Names
leucine-rich repeat serine/threonine-protein kinase 1
XP_014998668.2
XP_014998669.2
XP_014998670.2
XP_014998671.2
XP_028707176.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041760.1 Reference Mmul_10 Primary Assembly

    Range
    80209241..80363268
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015143183.2XP_014998669.2  leucine-rich repeat serine/threonine-protein kinase 1 isoform X1

    UniProtKB/TrEMBL
    F6XKP7, G7MWB5
    Conserved Domains (7) summary
    COG4886
    Location:302614
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    cd14067
    Location:12481523
    STKc_LRRK1; Catalytic domain of the Serine/Threonine Kinase, Leucine-Rich Repeat Kinase 1
    sd00033
    Location:304330
    LRR_RI; leucine-rich repeat [structural motif]
    sd00045
    Location:156186
    ANK; ANK repeat [structural motif]
    pfam16095
    Location:8441036
    COR; C-terminal of Roc, COR, domain
    pfam12796
    Location:126218
    Ank_2; Ankyrin repeats (3 copies)
    cl21455
    Location:639821
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  2. XM_015143185.2XP_014998671.2  leucine-rich repeat serine/threonine-protein kinase 1 isoform X2

    UniProtKB/TrEMBL
    G7MWB5
    Conserved Domains (7) summary
    COG4886
    Location:302614
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    cd14067
    Location:12481523
    STKc_LRRK1; Catalytic domain of the Serine/Threonine Kinase, Leucine-Rich Repeat Kinase 1
    sd00033
    Location:304330
    LRR_RI; leucine-rich repeat [structural motif]
    sd00045
    Location:156186
    ANK; ANK repeat [structural motif]
    pfam16095
    Location:8441036
    COR; C-terminal of Roc, COR, domain
    pfam12796
    Location:126218
    Ank_2; Ankyrin repeats (3 copies)
    cl21455
    Location:639821
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  3. XM_015143182.2XP_014998668.2  leucine-rich repeat serine/threonine-protein kinase 1 isoform X1

    UniProtKB/TrEMBL
    F6XKP7, G7MWB5
    Related
    ENSMMUP00000017517.4, ENSMMUT00000018702.4
    Conserved Domains (7) summary
    COG4886
    Location:302614
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    cd14067
    Location:12481523
    STKc_LRRK1; Catalytic domain of the Serine/Threonine Kinase, Leucine-Rich Repeat Kinase 1
    sd00033
    Location:304330
    LRR_RI; leucine-rich repeat [structural motif]
    sd00045
    Location:156186
    ANK; ANK repeat [structural motif]
    pfam16095
    Location:8441036
    COR; C-terminal of Roc, COR, domain
    pfam12796
    Location:126218
    Ank_2; Ankyrin repeats (3 copies)
    cl21455
    Location:639821
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  4. XM_015143184.2XP_014998670.2  leucine-rich repeat serine/threonine-protein kinase 1 isoform X1

    UniProtKB/TrEMBL
    F6XKP7, G7MWB5
    Conserved Domains (7) summary
    COG4886
    Location:302614
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    cd14067
    Location:12481523
    STKc_LRRK1; Catalytic domain of the Serine/Threonine Kinase, Leucine-Rich Repeat Kinase 1
    sd00033
    Location:304330
    LRR_RI; leucine-rich repeat [structural motif]
    sd00045
    Location:156186
    ANK; ANK repeat [structural motif]
    pfam16095
    Location:8441036
    COR; C-terminal of Roc, COR, domain
    pfam12796
    Location:126218
    Ank_2; Ankyrin repeats (3 copies)
    cl21455
    Location:639821
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  5. XM_028851343.1XP_028707176.1  leucine-rich repeat serine/threonine-protein kinase 1 isoform X1

    UniProtKB/TrEMBL
    F6XKP7, G7MWB5
    Conserved Domains (7) summary
    COG4886
    Location:302614
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    cd14067
    Location:12481523
    STKc_LRRK1; Catalytic domain of the Serine/Threonine Kinase, Leucine-Rich Repeat Kinase 1
    sd00033
    Location:304330
    LRR_RI; leucine-rich repeat [structural motif]
    sd00045
    Location:156186
    ANK; ANK repeat [structural motif]
    pfam16095
    Location:8441036
    COR; C-terminal of Roc, COR, domain
    pfam12796
    Location:126218
    Ank_2; Ankyrin repeats (3 copies)
    cl21455
    Location:639821
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
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